Chemotherapy plus radiation in advanced-stage endometrial cancer.

Hypothesis: We hypothesize that adjuvant radiation and chemotherapy improve the clinical benefit from treatment of advanced-stage endometrial adenocarcinoma.

Methods: We conducted a retrospective review of 125 patient with stage III or IVA endometrial adenocarcinoma who received adjuvant chemotherapy (n = 60) or chemoradiation (n = 65). Primary end points were rate of clinical benefit (ie, the percentage of patients who were alive and disease-free for at least 6 months after the last day of adjuvant treatment) and progression-free and overall survival.

Adjuvant treatment and survival in obese women with endometrial cancer: an international collaborative study.

Objective: The purpose of this study was to determine the impact of patient weight on the frequency of surgical staging lymphadenectomy and pelvic radiation. Adverse effects, disease relapse, and survival outcomes were investigated.

Study Design: Records of 766 women who underwent surgery for presumed corpus-confined endometrial cancer were reviewed.

Laparoscopic treatment of endometrial cancer: feasibility and results.

Objective: The aim of this study was to compare laparoscopic and abdominal approach in the treatment of endometrial cancer in our department.

Study Design: From January 1999 to November 2002, 77 patients underwent surgery for stages I-III endometrial cancer. The first group of 36 patients had abdominal hysterectomy as well as salpingo-oophorectomy, with or without lymphadenectomy.