Publications by authors named "Francesca DI Puppo"
Objective: Limited attention has been focused on the medical treatment of bowel endometriosis. This study evaluates the efficacy of administration of a continuous low-dose oral contraceptive in treating pain and other symptoms associated with colorectal endometriotic nodules, as evaluated by rectal endoscopic ultrasonography.
Design: Prospective observational study.
Endometriosis affects women of reproductive age, causing infertility and pain. Although immune cells are recruited in endometriotic lesions, their role is unclear. Tie2-expressing macrophages (TEMs) have nonredundant functions in promoting angiogenesis and growth of experimental tumors.
View Article and Find Full Text PDFAim: Endometriosis is defined by the presence of endometrial glands and stroma outside the uterus. The disease causes pelvic pain, dysmenorrhea, dyspareunia, dyschezia and urinary symptoms. The aim of this study was to assess the usefulness of endoscopic ultrasound (EUS) and elastosonography for detecting rectosigmoid endometriosis and to compare the findings, in selected and symptomatic patients, with surgical specimens in order to select the best surgical strategy.
View Article and Find Full Text PDFThe mechanisms that sustain endometrial tissues at ectopic sites in patients with endometriosis are poorly understood. Various leukocytes, including macrophages, infiltrate endometriotic lesions. In this study, we depleted mouse macrophages by means of either clodronate liposomes or monoclonal antibodies before the injection of syngeneic endometrial tissue.
View Article and Find Full Text PDFArticle Synopsis
- Whipple's disease is a recurring infectious condition likely caused by the bacteria Tropheryma whippelii, diagnosed through specific tissue features and PCR testing.
- A case study of a 23-year-old woman highlights symptoms such as encephalopathy, neuropathy, high fever, and hormonal imbalance, leading to amenorrhea.
- The discussion suggests that her hormonal issues may result from either prolonged high fever damaging ovarian function or the presence of the bacteria in ovarian tissue.