Publications by authors named "Francesca Coppola"

According to the FAO/WHO guidelines, selection of probiotics requires the assessment of survival under gastrointestinal stress and adhesion to human epithelial cells. These attributes were evaluated on ATCC BAA-835 simulating the gastrointestinal transit (GIT) immediately followed by adhesion to human intestinal cell lines (CaCo2, HT-29, and HT-29-MTX) as an alternative approach to methods performed with fresh cells in each trial. The survival rate after GIT, as determined by plate counts and fluorescent probes, was significantly higher for (about 8 Log CFU/mL) than for the probiotic GG ATCC 53103 (about 3 Log CFU/mL).

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  • * Two fat replacers, lemon albedo and carob seed gum, were analyzed for their effects on the burgers, along with plant extracts from nettle leaves and medlar seeds that were tested for antimicrobial and antioxidant properties.
  • * Results showed that while the fat replacers improved nutrition and taste, they did not guarantee safety, indicating that combining them with natural antimicrobial extracts, like medlar seeds, is crucial for producing safe low-fat burgers.
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Our work investigated the antimicrobial and prebiotic properties of basil, mint, oregano, rosemary, savory, and thyme honey. The potential antimicrobial action, assessed against the pathogens , , , , and , evidenced the capacity of the honey to influence the pathogenic hydrophobicity and hemolytic activities. Honey inhibited pathogen biofilms, acting especially on the mature biofilms, with inhibition rates of up to 81.

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  • The study investigates the healthy properties of bee pollen based on its source and storage conditions, specifically analyzing samples from two areas in Tuscany.
  • The analysis revealed that non-terpene derivatives, particularly aldehydes, were the most common volatile compounds, with clear differences based on how the samples were stored.
  • Panel tests showed that bee pollen from the suburban area lacked attractiveness, and those stored at room temperature had the poorest sensory qualities compared to other storage conditions.
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A single strain of yeast was isolated from industrial gluten bread (GB) purchased from a local supermarket. This strain is responsible for spoilage consisting of white powdery and filamentous colonies due to the fragmentation of hyphae into short lengths (dust-type spots), similar to the spoilage produced by chalk yeasts such as , and . The isolated strains were identified initially by traditional methods as , but with genomic analysis, they were definitively identified as , a rare ascomycetous opportunistic yeast species with low virulence attributes, uncommonly implicated in bread spoilage.

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  • Researchers studied spoiled cooked sausages with yellow stains to identify the microbial cause and test antimicrobials to prevent spoilage.
  • They found that a specific bacteria was responsible for the yellow coating and that this bacteria thrived in the presence of cooked sausage extract, producing volatile compounds typical of spoilage.
  • While several antimicrobials slowed the bacteria's growth, only hop extract completely inhibited it without affecting the sausages' taste, marking a new finding in antimicrobial research.
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Honeybees ( L.) have to face many challenges, including infestation, associated with viral transmission. Oxalic acid is one of the most common treatments against .

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  • Pharmaceuticals like caffeine (CAF) enter aquatic ecosystems mainly through wastewater and hospital waste, raising concerns about their environmental impact, especially under rising temperatures caused by climate change.
  • The study used the mussel Mytilus galloprovincialis to examine the toxicity of different CAF concentrations at 17 °C and 21 °C, observing subcellular effects over 28 days.
  • Findings revealed that higher CAF levels at 17 °C increased metabolism and caused cellular damage, while at 21 °C, the mussels showed antioxidant enzyme induction but still suffered from cellular damage, with a synergistic negative effect when CAF exposure and temperature rise occurred together.
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  • Interspecific transmission of pathogens among wild bees is primarily influenced by honey bee (Apis mellifera) colonies, which act as reservoirs for these pathogens, leading to significant concerns for wild bee populations in Italy due to limited data availability.
  • A study sampled 3,372 bees across 11 Italian regions, finding that 68.4% were infected with at least one pathogen, with DWV, BQCV, N. ceranae, and CBPV being the most common.
  • The research identified that factors such as meteorological conditions and agricultural practices have a larger impact on pathogen spread than apiary density, highlighting the need for conservation efforts to protect wild bee health and populations.
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  • Caulerpin (CAU) is a bioactive compound from invasive green algae, while caffeine (CAF) is a common water pollutant and psychoactive substance. Both can accumulate in aquatic life and in human diets.
  • The study used mussels (Mytilus galloprovincialis) to explore potential interactions between CAU and CAF, finding that CAF induced toxic effects, but CAU did not worsen these effects or cause cumulative damage.
  • The results suggest CAU may help reduce CAF toxicity due to its potential role in detoxification processes, encouraging more research into its possible use as a food additive for clearing pollutants from the body.
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Searching for artificial diets positively affecting the survival, immune and antioxidant systems of honey bees is one of main challenges occurring in beekeeping. Among nutrients, lipids play a significant role in insect nutrition as structural components in cell membranes, energy sources and reserves, and are involved in many physiological processes. In this context, the aim of this work was to investigate the effect of 0.

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The Ria de Aveiro is an important coastal lagoon for wildlife in Portugal, where the production of bivalves reaches approximately 2700 tons annually. However, the illegal overfishing of bivalves is frequent in this lagoon, which causes critical changes in the ecosystem. In this study, using a developed food-web model (Ecopath model), the ecological carrying capacity (ECC) and maximum sustained yield (MSY) of the Manila clam, Ruditapes philippinarum were estimated, and the effects of further increases in clam biomass on other species were investigated.

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  • Royal Jelly, a nutrient-rich secretion from nurse bees, is gaining attention as a functional food, but there's limited information on its chemical stability and enzymatic activity over time.
  • This study examined the effects of refrigeration and freezing on the activity of several enzymes in Royal Jelly over different storage durations, finding that refrigeration led to a significant decline in enzyme activity after one year.
  • The findings suggest that freezing preserves enzyme activity better than refrigeration, making it a preferable storage method for maintaining Royal Jelly freshness, while further research is needed to explore enzyme degradation and activity trends over longer periods.
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The concentration of nanoplastics (NPs) is expected to increase in aquatic environments thus potentially threatening freshwater organisms through interactions with plastic particles that variously float, circulate in the water column or sink into the benthos. Studies into the mechanisms of any NP effects are still scarce, particularly with respect to the regenerative ability of biota for which there is no recognised model organism. The present study therefore aimed to investigate behavioural and regeneration responses of the freshwater planarian Girardia tigrina after 10 days exposed to along a gradient 0.

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  • Bioactive compounds from marine invasive species, like the alkaloid caulerpin (CAU) from the invasive green algae Caulerpa cylindracea, can have significant effects on native marine life, similar to the synthetic drug fenofibrate (FFB), which poses risks to aquatic ecosystems.
  • A study comparing the effects of CAU and FFB on the mussel species Mytilus galloprovincialis showed that FFB resulted in metabolic impairments and cellular damage, while CAU did not lead to significant adverse effects.
  • Findings suggest that while FFB is harmful and its release should be minimized, CAU could be a potential resource for utilizing invasive species without detrimental impacts on marine life.
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(Meigen, 1838) is a Sarcophagid dipteran endoparasitoid of L., and myiasis, caused by this fly, is reported in several European, North African and Middle Eastern countries. Nevertheless, very little knowledge concerning the aggression and parasitisation behavior of toward is available in the scientific literature, and the temporal pattern of aggression remains unclear.

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The crested porcupine is a frequent host species in wildlife rescue centers and no guidelines for its management, liberation and post-liberation monitoring are yet available. Here, captive-grown porcupines' behavior and survival in the wild after liberation were investigated and described for the first time. Management strategies adopted at the centers could affect porcupine adaptation to the natural environment.

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  • Latr. bees are crucial for pollinating orchard crops, supporting healthy ecosystems and providing economic benefits.
  • The study investigates how delaying the emergence of bees affects their mating behaviors by comparing those that emerge naturally and those that emerge later.
  • Findings show that both groups exhibit similar mating patterns, but older bees tend to have more short copulations, which might hinder successful reproduction.
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  • - Personal care products (PCPs) like soaps and shampoos are commonly found in water systems but their impact on wildlife, particularly mussels, is not well understood.
  • - The study looked at how different temperatures (17 ºC and 22 ºC) and levels of Sodium Lauryl Sulfate (SLS) (0 mg/L vs. 4 mg/L) affect the health of the mussel Mytilus galloprovincialis, focusing on metabolic and oxidative stress responses.
  • - Results showed that mussels exposed to SLS had worse health, and higher temperatures worsened these effects, indicating that M. galloprovincialis could serve as a valuable indicator of pollution from PCPs along with the impacts
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Expansion of wild and managed allochthonous species leads to potential negative consequences for the endemic wildlife, such as resource competition, pathogens spread, hybridization and native species replacements. On Capraia Island, the last sighting of Bombus terrestris terrestris dates back to 1917. All subsequent surveys carried out on the island only reported the presence of B.

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  • Mercury, cobalt, and nickel are toxic metals found in various products, which pose significant risks to vulnerable ecosystems and have primarily been studied individually, neglecting their combined effects in polluted environments.
  • The study investigated how the mussel Mytilus galloprovincialis responds to individual and combined exposures of these metals over 28 days, measuring their accumulation and effects on metabolic and oxidative stress biomarkers.
  • Findings revealed that while mussels accumulated metals, exposure to the mixture resulted in greater negative impacts than individual metals, demonstrating the need for risk assessments that consider metal interactions and their complex biological effects.
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  • Benign renal tumors like renal oncocytoma (RO) can be misdiagnosed as malignant renal cell carcinomas (RCC) due to similar imaging characteristics, prompting the need for better diagnostic systems using machine learning and radiomic features.* -
  • A study analyzed CT images from 77 patients, extracting features from tumor volumes and surrounding transition zones (ZOT), and used a genetic algorithm to select the most effective features to build a decision tree classifier for distinguishing RO from clear cell RCC (ccRCC).* -
  • Results showed that ZOT features were the most predictive, with the best model achieving a ROC AUC score of 0.87 when feature selection was applied to the entire dataset, while the version
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  • Locally Recurrent Rectal Cancer (LRRC) is a serious condition that can invade surrounding pelvic organs, making early diagnosis crucial for effective treatment.
  • The study used radiomic analysis to enhance imaging detection methods, specifically through CT and PET/CT scans, by evaluating quantitative tissue properties for better differentiation of LRRC.
  • Out of 563 patients, 57 suspected LRRC cases were analyzed, and specific radiomic features were identified that can significantly distinguish LRRC from non-LRRC cases, highlighting the importance of these techniques in improving diagnostic accuracy.
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Gastrointestinal nematodes and protozoa and other parasite occurrences were evaluated in free-ranging wolf () and red fox () populations from natural and anthropized areas of Central Italy. Analyzed fecal samples were collected from 60 foxes and 40 wolves in the anthropized areas, and 41 foxes and 39 wolves in the natural areas. In foxes, hookworm infections ( < 0.

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