Publications by authors named "Francesca Cefaloni"
Background/objectives: Benralizumab is a monoclonal antibody that targets the interleukin-5 receptor (IL-5Rα), leading to the rapid depletion of blood eosinophils. RCTs have demonstrated efficacy in patients with severe eosinophilic asthma (SEA). The aim of this study was to assess the efficacy of benralizumab on sinonasal outcomes in a real-life setting in patients with SEA and concomitant chronic rhinosinusitis with nasal polyps (CRSwNP).
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- Guidelines for treating asthma exacerbations typically recommend bronchodilators and corticosteroids, but antibiotic use is often overlooked despite frequent prescriptions in practice.
- A survey involving 252 healthcare professionals revealed a 19% antibiotic prescription rate for asthma exacerbations, with significant variation among different specialties like pediatrics, pulmonology, general practice, and allergy.
- The study highlights the need for evidence-based guidelines to ensure more rational use of antibiotics in treating asthma exacerbations, especially considering factors like purulent sputum, fever, and comorbidities that influence prescription decisions.
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread worldwide since December 2019, causing the COVID-19 pandemic. Several measures have taken place in many countries to avoid further spread of the virus and to manage infected people according to disease severity. Notably, telemedicine (TM) was successfully used to manage less severe patients.
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