Publications by authors named "Francesca Caroppo"
While atypical, the development of psoriatic plaques over vascular malformations in children is plausible and should not necessarily prompt clinicians to perform costly or invasive procedures.
View Article and Find Full Text PDFThis study, employing an interim analysis, investigates the effects of the Dermamecum protocol, a structured educational and tailored approach that stratifies ostomy patients into risk paths (green, yellow, red) based on pre-operative and post-operative characteristics. The green path indicates a low risk of peristomal skin complications (PSCs), focusing on sustaining healthy behaviours and basic stoma care. The yellow path represents a moderate risk, emphasizing the need for patients to self-monitor and recognize early signs of complications.
View Article and Find Full Text PDFArticle Synopsis
- * The systematic literature review analyzed six relevant studies from a total of 64, examining the effectiveness of these treatments on nine patients, highlighting benefits like long-term tissue remodeling and improved skin aesthetics.
- * The findings suggest that the combination of laser therapy and fillers could enhance treatment for LS patients, indicating a need for more research to develop a solid clinical approach and improve patient quality of life.
Article Synopsis
- Atopic dermatitis (AD) affects about 14.8% of adolescents and can negatively impact their sleep, academic performance, mood, self-esteem, and social interactions.
- Upadacitinib was recently approved for treating moderate-to-severe AD in adolescents 12 years and older, and this real-world study aimed to assess its effectiveness and safety.
- The study found significant improvements in the severity of AD among patients treated with upadacitinib over 52 weeks, with most achieving substantial reductions in symptoms and good overall safety outcomes.
Impact of itching, burning and pain in children with psoriasis: An observational monocentric study.
J Eur Acad Dermatol Venereol
November 2024
Article Synopsis
- Hypersensitivity reactions (HR) are common in mastocytosis, a condition analyzed using data from the European Competence Network on Mastocytosis (ECNM), involving 2485 adults.
- About 38.1% of patients reported HR, with Hymenoptera venoms being the primary trigger for cutaneous mastocytosis and indolent systemic mastocytosis, while drug reactions were more common in advanced systemic mastocytosis.
- Key risk factors for HR include lower tryptase levels, minimal mast cell infiltration in bone marrow, and a diagnosis of indolent systemic mastocytosis, with new reactions occurring in 4.8% of patients over four years.
Allergic contact dermatitis (ACD) is a common inflammatory skin disease caused by delayed hypersensitivity to chemical and biotic contact allergens. ACD significantly affects the patients' quality of life negatively impacting both occupational and non-occupational settings. Patch testing is the gold standard diagnostic in vivo test to precise the ACD etiology and to correctly perform prevention.
View Article and Find Full Text PDFCertain laboratory abnormalities correlate with subvariants of systemic mastocytosis (SM) and are often prognostically relevant. To assess the diagnostic and prognostic value of individual serum chemistry parameters in SM, 2607 patients enrolled within the European Competence Network on Mastocytosis and 575 patients enrolled within the German Registry on Eosinophils and Mast Cells were analyzed. For screening and diagnosis of SM, tryptase was identified as the most specific serum parameter.
View Article and Find Full Text PDFArticle Synopsis
- Psoriasis is a common skin condition that typically appears in areas of friction, but when it affects the lips, it's rare and often misdiagnosed.
- Despite various anti-psoriatic treatments available, most evidence comes from limited case studies with incomplete results.
- A 14-year-old boy with lip psoriasis was treated successfully with adalimumab, leading to complete remission after 6 months.
We present a case of sirolimus-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a stem cell transplant patient. Sirolimus is an immunosuppressive drug that inhibits the mammalian target of rapamycin (mTOR) pathway. A 24-year-old male with a history of acute lymphoblastic leukemia (ALL) underwent testicular extraction followed by hematopoietic stem cell transplantation (HSCT).
View Article and Find Full Text PDFWe present the case of a child developing widespread vesicle-bullous lesions during an acute and symptomatic Epstein-Barr Virus infection. Antibody serology, biopsy, and direct immunofluorescence allowed the diagnosis of a paraviral bullous eruption. To our knowledge, this is the first report of bullous eruption following Epstein-Barr virus infection in childhood.
View Article and Find Full Text PDFPatients with a stoma are at risk of developing peristomal skin complications (PSCs) that can negatively impact their quality of life. This study aims to identify potential risk factors for dermatitis, pruritis/xerosis, infections, and ulcerations among patients with a stoma and evaluate preventive measures. This cross-sectional study involved data regarding 232 Italian patients with a stoma.
View Article and Find Full Text PDFArticle Synopsis
- - A newborn was diagnosed with trichothiodystrophy-3 (TTD3) due to a new homozygous variant in the GTF2H5 gene.
- - The patient's severe symptoms included congenital ichthyosis, serious brain anomalies, life-threatening infections, bilateral cryptorchidism, and a rare complex heart defect.
- - This case highlights the unusual severity and complexity of TTD3 symptoms, particularly the associated cardiac malformation not seen in previous TTD3 patients.
Article Synopsis
- The study investigates the dermatological manifestations of COVID-19 in children, particularly noting the prevalence of chilblain-like lesions among infected and non-infected patients, attributed to a pronounced interferon response in younger individuals.
- Conducted over six months, the research involved 137 patients aged 1 to 18 from 23 Italian dermatological units, who exhibited a variety of skin lesions primarily on the feet.
- Results showed diverse skin symptoms, with many experiencing concomitant systemic symptoms, highlighting the complex interplay of dermatological and respiratory issues related to COVID-19 in children.
Background: Occupational skin diseases have led the occupational disease statistics in Europe for many years. Especially occupational allergic contact dermatitis is associated with a poor prognosis and low healing rates leading to an enormous burden for the affected individual and for society.
Objectives: To present the sensitization frequencies to the most relevant allergens of the European baseline series in patients with occupational contact dermatitis (OCD) and to compare sensitization profiles of different occupations.