Publications by authors named "Francesc Tresserra Casas"
[SEAP-IAP recommendations for the collection, storage and use of biological materials of human origin and related data intended for research. Generic biobank consideration and ethical-legal review (Part II)].
Rev Esp Patol
October 2024
The working group set up by the SEAP-IAP addresses in this Part II some general considerations and five particular considerations to be taken into account when a biological sample of human origin, coming from our archives, acquires a different destination from the usual one, in this case for research. From this moment on, we must follow mandatory legal and ethical rules, and the different recitals provide us with guidelines to ensure good practice, both for biological material and its associated data. The traditional task of custody given to the Pathological Anatomy is approached, as always, from the point of view of responsibility and, in this article, adjusted to its time.
View Article and Find Full Text PDF[Times and conditions of storage of samples in anatomic pathology. Recommendations of the Spanish Society of Anatomic Pathology (SEAP) part 1: samples for diagnosis].
Rev Esp Patol
October 2024
Article Synopsis
- Proper storage of pathology specimens is crucial for patient safety, but there are no established guidelines detailing the minimum storage duration for samples.
- A working group from the Spanish Society of Anatomic Pathology reviewed literature and drew up recommendations after discussions and voting.
- The established minimum storage times include at least 10 years for paraffin embedded blocks and histological preparations, 3 years for cervico-vaginal cytology, and 5 years for extracted nucleic acids, among other classifications.
Brain metastases constitute a challenge in the management of patients with HER2-positive breast cancer treated with anti-HER2 systemic therapies. Here we sought to define the repertoire of mutations private to or enriched for in HER2-positive brain metastases. Massively parallel sequencing targeting all exons of 254 genes frequently mutated in breast cancers and/or related to DNA repair was used to characterize the spatial and temporal heterogeneity of HER2-positive breast cancers and their brain metastases in six patients.
View Article and Find Full Text PDF•A simple endometriosis can result in malignancy pathology, as a neoplasia.•Wall-abdominal tumors and soft tissue as a possible differential diagnosis of abdominal wall endometriosis•Preperitoneal node-metastasis as malignancy of endometriosis in previous cesarean scar.
View Article and Find Full Text PDFBackground: Our aim was to evaluate and compare lymph node involvement, as well as disease-free survival (DFS) and overall survival (OS), between infiltrating ductal carcinoma with (group 1) and without (group 2) intraductal carcinoma component in order to determine the prognostic value of the intraductal component.
Methods: Data from 389 cases of infiltrating ductal carcinoma of the breast were included in the study by means of reviewing medical charts and pathology slides.
Results: There was no statistically significant difference between both groups regarding node status.
Background: Studies have shown that breast infiltrating ductal carcinoma develops from precursor lesions or pre-invasive. It is accepted that the risk of invasive ductal carcinoma increased slightly in hyperplasia, but especially in cases of atypical hyperplasia and intraductal carcinoma.
Objectives: To evaluate and compare the nodal status between ductal breast cancer with in situ component (group 1) or without it (group 2).