Publications by authors named "Francesc Olivares"

Article Synopsis
  • The study aimed to investigate the relationship between low HLA-I expression, NK cell infiltration, and various prognostic features in breast cancer, particularly in relation to axillary lymph node (ALN) infiltration.
  • It involved a retrospective analysis of 35 breast cancer patients with axillary infiltration, correlating HLA-I H-scores and NK cell counts with several pathological variables from surgical specimens.
  • Results indicated that higher HLA-I H-scores were associated with features of poor prognosis, such as increased histological grade and Ki67 expression, but not with the degree of ALN infiltration, suggesting unique characteristics of luminal breast cancer compared to other cancers.
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Stromal tumor-infiltrating lymphocytes (sTILs) are a robust prognostic and predictive biomarker in triple-negative breast carcinoma. However, the sTIL compartment comprises different cell populations. The aim of the study is to characterize the distribution of T cells (CD3+ and CD8+), B cells, and plasma cells and explore their association with outcome in the surgical specimen of 62 patients.

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Purpose: Mycobacterium bovis bacillus Calmette-Guérin is the most effective treatment for high risk noninvasive bladder cancer. Although bacillus Calmette-Guérin immunotherapy clearly decreases recurrence and progression rates, side effects are common and infection with the bacillus has been described. For these reasons it is necessary to find safer alternatives to the live bacillus.

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In low-income countries some infections caused by nontuberculous mycobacteria are misdiagnosed as multidrug-resistant tuberculosis. In most of these settings the observation of microscopic cords is the only technique used to identify Mycobacterium tuberculosis in the laboratory. In this article we definitively demonstrate that Mycobacterium abscessus, an emerging pulmonary pathogen, also forms microscopic cords.

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