Impact of a Novel Strategy for Critical Values Communication for the Management of Patients Treated with Clozapine.

Introduction: Clozapine is an antipsychotic drug used to treat resistant schizophrenia and other disorders. Based on the actual Spanish legislation, patients treated with clozapine must undergo periodical haematological examinations and treatment should be reviewed when the haemogram shows either a leukocyte count of ≤ 3500/mm or neutrophil count < 2000/mm. An automatic notification system has been developed to optimize patient management and it's utility was assessed following the implementation of the new system.