The effects of vitamin C supplementation on incident and progressive knee osteoarthritis: a longitudinal study.

Objective: To evaluate the association between vitamin C supplementation and the incidence and progression of radiographic knee osteoarthritis (OA).

Design: Prospective cohort study.

Setting: Clearwater Osteoarthritis Study (COS): (1988 to the present) a longitudinal study.

Job-related osteoarthritis of the knee, foot, hand, and cervical spine.

Objectives: To assess the influence of occupational exposures on risk of site-specific radiographic osteoarthritis (OA) of the knee, hand, foot, and cervical spine.

Methods: Using a cross-sectional design, data collected from men and women aged 40 years and older participating in the Clearwater Osteoarthritis Study were analyzed (n = 3436). Subjects' occupational exposures were queried using the study intake form, including stair climbing, standing on a rigid surface, squatting, and jolting.

Radiographic cervical spine osteoarthritis progression rates: a longitudinal assessment.

Relative to other sites, the cervical spine has received little attention in the osteoarthritis (OA) literature. Using data from a longitudinal study, we provide age-specific progression rates of radiographic cervical spine OA, by gender. Data from cohort subjects (ages 40+) from the Clearwater Osteoarthritis Study were analyzed (N = 707).

The association of BMI and knee pain among persons with radiographic knee osteoarthritis: a cross-sectional study.

Background: Many people with radiographic knee osteoarthritis (RKOA) do not present with pain. It is suspected that such persons tend toward lower body mass index (BMI). The purpose of the study was to explore the relationship between BMI and knee pain among persons with RKOA.

Exercise and hand osteoarthritis symptomatology: a controlled crossover trial.

Study Design: Randomized Clinical Trial.

Introduction: Hand exercises have been recommended as treatment for hand osteoarthritis (OA) but research evidence is sparse.

Purpose Of The Study: To investigate effects of daily 16-week home-based hand exercise among persons with hand OA.

The effects of strength training among persons with hand osteoarthritis: a two-year follow-up study.

Hand exercise is recommended for hand osteoarthritis (OA) management, but few efficacy studies have been published. The purpose of the study was to determine the effects of two years of whole body strength training and gripper exercise on hand strength, pain, and function in adults with radiographic evidence of hand OA. Older adults (N=55; 71.

Positive hindfoot valgus and osteoarthritis of the first metatarsophalangeal joint.

Background: The aim of this retrospective cohort study was to evaluate the association between increased hindfoot valgus and the subsequent development of osteoarthritis of the first metatarsophalangeal (MTP) joint. Specifically, our hypothesis was that among individuals free from first MTP joint osteoarthritis, those who have positive hindfoot valgus are more likely to develop first MTP joint osteoarthritis than are those individuals with normal hindfoot alignment.

Methods: Our sample consisted of 1592 men and women, 40 years of age or older, participating in the Clearwater Osteoarthritis Study (1988 to 2001).

Exercise and osteoarthritis: are we stopping too early? findings from the Clearwater Exercise Study.

The value of exercise for people with knee osteoarthritis (OA) receives continuing consideration. The optimal length of study follow-up time remains unclear. A group of individuals with knee OA participating in an exercise intervention was followed for 2 years.

Effect of regular exercise on the radiographic progression of foot osteoarthritis.

Among the elderly, osteoarthritis often causes chronic pain and disability. Although research has addressed the association between exercise and osteoarthritis, few studies have examined the effect of exercise on the radiographic progression of osteoarthritis. We investigated the relationship between ongoing exercise and radiographic progression of foot osteoarthritis.

The association of radiographic foot osteoarthritis and radiographic osteoarthritis at other sites.

Objective: To quantify the association between radiographic foot osteoarthritis (OA) and radiographic OA at four joints: second distal interphalangeal (DIP), third proximal interphalangeal (PIP), first carpometacarpal (CMC), and the knee.

Methods: Data collected for the Clearwater Osteoarthritis Study (COS) were analyzed (N=3436). The study outcome was first metatarso-phalangeal joint (first MTP) OA status.

The association between medication usage and dropout status among participants of an exercise study for people with osteoarthritis.

Background And Purpose: Little is known about predictors of dropout status in exercise studies for people with osteoarthritis. Losses to follow-up can pose serious threats to study validity. The purpose of this study was to assess the ability of arthritis medication usage the month prior to enrollment to predict dropout status among participants in an exercise study for people with osteoarthritis.