Publications by authors named "Frances Chen"

The current study examines the relationship between polyvictimization and academic performance in college across gender and sexual identity. Participants were from the Spring 2019 administration of the American College Health Association's National College Health Assessment-II. Multinomial logistic regression models and negative binomial regression models with and without interaction terms were used to explore if gender and sexual identity are related to academic performance, and if they are differentially related to academic performance when experiencing polyvictimization.

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Dogs have played an outsized role in the field of behavioral genetics since its earliest days. Their unique evolutionary history and ubiquity in the modern world make them a potentially powerful model system for discovering how genetic changes lead to changes in behavior. Genomic technology has supercharged this potential by enabling scientists to sequence the DNA of thousands of dogs and test for correlations with behavioral traits.

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Objectives: Late adolescence (15-19 years) is a period of heightened susceptibility to stress, but regular physical activity may attenuate reactivity to stressors. We aimed to explore the effects of physical activity intensity on older adolescents' stress-reactivity and self-reported mental health.

Design And Methods: Three-arm randomised controlled trial in New South Wales, Australia (April-June 2021).

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While liquid biopsy has potential to transform cancer diagnostics through minimally-invasive detection and monitoring of tumors, the impact of preanalytical factors such as the timing and anatomical location of blood draw is not well understood. To address this gap, we leveraged pet dogs with spontaneous cancer as a model system, as their compressed disease timeline facilitates rapid diagnostic benchmarking. Key liquid biopsy metrics from dogs were consistent with existing reports from human patients.

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Moral disengagement (MD) has been consistently associated with antisocial behavior (ASB) in prior research. Limited research tested the directionality of the bivariate relationship, and most studies focused only on the direction of MD predicting ASB, even though ASB could also influence MD based on the literature on attribution and behavioral influence on attitude. Moreover, the few studies testing reciprocal associations rarely controlled for stable individual differences and did not explicitly examine the age effect to allow for a clear developmental inference.

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Loneliness is common and, while generally transient, persists in up to 22% of the population. The rising prevalence and adverse impacts of chronic loneliness highlight the need to understand its underlying mechanisms. Evolutionary models of loneliness suggest that chronically lonely individuals demonstrate negative interpretation biases towards social information.

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Callous-unemotional (CU) traits have important utility in distinguishing individuals exhibiting more severe and persistent antisocial behavior, and our understanding of reward processing and CU traits contributes to behavioral modification. However, research on CU traits often investigated reward alongside punishment and examined solely on average reward reactivity, neglecting the reward response pattern over time such as habituation. This study assessed individuals' pre-ejection period (PEP), a sympathetic nervous system cardiac-linked biomarker with specificity to reward, during a simple reward task to investigate the association between CU traits and both average reward reactivity and reward response pattern over time (captured as responding trajectory).

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Autistic traits are associated with differential processing of emotional and social cues. By contrast little is known about the relationship of autistic traits to socio-emotional memory, though research suggests an integral relationship between episodic memory processes and psychosocial well-being. Using an experimental paradigm, we tested if autistic traits moderate the effects of negative emotion and social cues on episodic memory (i.

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Though considerable work supports the Dimensional Model of Adversity and Psychopathology, prior research has not tested whether the dimensions-threat (e.g., abuse) and deprivation (e.

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Integrating Polyvagal Theory and Reinforcement Sensitivity Theory (RST), we examined pre-ejection period (PEP) reward reactivity, which was suggested to index trait impulsivity, as a moderator between respiratory sinus arrhythmia (RSA) reactivity and antisocial behavior (ASB), and substance use in an urban male, adult sample. To understand the inconsistent findings between RSA reactivity and externalizing problems, we proposed to study both negatively and positively valenced tasks for RSA reactivity and to include PEP reward reactivity as a moderator for the RSA-behavior link. Data were collected from an urban sample of 131 male adults (active offenders, demographic controls, and college students).

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We argue that i-frame interventions can and do increase support for systemic reforms, and s-frame interventions should be pursued in parallel to address key societal issues. Without accompanying i-frame interventions, s-frame interventions can fail. We offer an operant conditioning framework to generate positive spillover effects.

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Article Synopsis
  • Domestic dogs exhibit a variety of hereditary behaviors shaped by human selection, presenting a unique opportunity to study genetics related to human neuropsychiatric disorders.
  • The review discusses the range of dog behaviors, sources of behavioral selection, and advancements in canine behavioral genetics, emphasizing their relevance as a genomic model.
  • Two key areas of focus are age-related cognitive decline and compulsive disorders in dogs, which may provide valuable insights for understanding complex behaviors in humans and support community science initiatives.
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The detrimental effects of loneliness and social isolation on health and well-being outcomes are well documented. In response, governments, corporations, and community-based organizations have begun leveraging tools to create interventions and policies aimed at reducing loneliness and social isolation at scale. However, these efforts are frequently hampered by a key knowledge gap: when attempting to improve specific health and well-being outcomes, decision-makers are often unsure whether to target loneliness, social isolation, or both.

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Parentification occurs when youth are forced to assume developmentally inappropriate parent- or adult-like roles and responsibilities. This review thoroughly examines current empirical research on parentification, its outcomes, and related mechanisms to outline patterns of findings and significant literature gaps. This review is timely in the large context of the COVID-19 pandemic, when pandemic-induced responsibilities and demands on youth, and the shifting family role may exacerbate parentification and its consequences.

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Article Synopsis
  • Developing reliable tools to assess factors like frailty and health-related quality of life (HRQL) is vital for understanding aging in dogs and can also inform research on human aging.
  • In a study involving 451 adult dogs, researchers validated the Canine Frailty Index (CFI) and VetMetrica HRQL tools, showing that older dogs (7 years and up) exhibit higher frailty and lower HRQL compared to younger dogs (2-6 years).
  • The study found that body size didn't significantly affect frailty or HRQL scores, but larger, older dogs had a quicker decline in owner-reported activity and comfort levels, highlighting the need for these tools in advancing dog healthspan research and gerotherapeutics for
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Aging is the leading cause of disability, disease, and death in adult dogs. One major consequence of aging is diminishing physical function. For normal functioning, basic elements such as strength, balance, and energy must be present.

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Research suggests that various indicators of hypothalamic pituitary adrenal (HPA) axis activity prospectively predict depression, but few studies have evaluated whether trait indicators of HPA axis activity are related to depression. Further, no prior study has examined links between trait cortisol and psychopathology using a trait indicator that captures HPA axis activity over multiple time points. Here we examined whether we could construct an across-wave latent trait cortisol (LTC) factor using cortisol samples collected over 13 weeks, and whether the across-wave LTC prospectively predicted new depressive symptom onsets and symptom duration.

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Writing-based psychological interventions have been widely implemented to produce adaptive change, e.g., through self-affirmation (reminding people of their most important values).

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While growing evidence documents strong associations between volunteering and improved health and well-being outcomes, less is known about the health and well-being factors that lead to increased volunteering. Using data from 13,771 participants in the Health and Retirement Study (HRS)-a diverse, longitudinal, and national sample of older adults in the United States-we evaluated a large range of candidate predictors of volunteering. Specifically, using generalized linear regression models with a lagged exposure-wide approach, we evaluated if changes in 61 predictors spanning physical health, health behaviors, and psychosocial well-being (over a 4-year follow-up between t; 2006/2008 and t; 2010/2012) were associated with volunteer activity four years later (t; 2014/2016).

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Transitional aged youth (18-24) report increasing and peaking risk-taking (sexual, substance, and delinquent behavior). Stressful life events (SLE) are associated with these risk-taking behaviors. Little is known regarding what mediates these relationships.

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Prior study has found that the interplay of the hypothalamic-pituitary-adrenal (HPA) axis and the autonomic nervous system (ANS) influences behavior problems in youth. Yet, little is known regarding this relationship in adults and traits related to the coordination of the stress systems. This study aims to extend the findings of a youth sample that the coordination between HPA and ANS, measured as cortisol and alpha-amylase (AA) respectively, was associated with antisocial behavior in adults.

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Biological aging is the single most important risk factor for disease, disability, and ultimately death in geriatric dogs. The effects of aging in companion dogs also impose significant financial and psychological burdens on their human caregivers. The underlying physiologic processes of canine aging may be occult, or early signs of aging may be ignored because of the misconception that biological aging is natural and therefore inevitable.

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Aging is the single most important cause of disease, disability, and death in adult dogs. Contrary to the common view of aging as a mysterious and inevitable natural event, it is more usefully understood as a set of complex but comprehensible biological processes that are highly conserved across species. Although the phenotypic expression of these processes is variable, there are consistent patterns both within and between species.

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The Cognitive, Affective and Somatic Empathy Scales (CASES) assess three forms of empathy, each with subscales for positive and negative empathy. The present study extends this child instrument to adults and examines its factor structure and construct validity. A secondary aim is to investigate the under-researched area of positive empathy.

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Background: The incidence of depression in human females rises steadily throughout adolescence, a critical period of pubertal maturation marked by increasing levels of gonadal hormones including estrogens and progesterone. These gonadal hormones play a central role in social and emotional development and may also contribute to the increased occurrence of depression in females that begins in early adolescence. In this study, we examine whether and how introducing synthetic estrogen and progestin derivatives through the use of combined hormonal contraceptives (CHC), affects adolescent females' risk for developing depression.

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