Relationships of serum leptin to clinical and anthropometric findings in obese patients.

Background: The authors evaluated the relationship between leptin and the clinical, anthropometric and metabolic variables connected to the metabolic syndrome in obese individuals.

Methods: A large group of patients with different degrees of obesity was investigated: body mass index (BMI) values, serum leptin, fasting glucose and insulin, triglycerides and HDL-cholesterol concentrations, insulin resistance index and blood pressure were measured.

Results: On multiple regression analysis, serum leptin levels appeared to be positively correlated to the BMI and to the serum HDL-cholesterol concentration.

Serum leptin level and restrained eating: study with the Eating Disorder Examination.

Serum leptin concentrations in obese patients are influenced at short-term by a reduction of food intake. The objective of this investigation was to evaluate the relationship between serum leptin level and eating behavior. The eating behavior and the food and shape attitudes of a group of obese women were assessed by the Eating Disorder Examination (EDE), and the subscale scores were correlated with serum leptin levels.