Publications by authors named "Franca Borella"
Article Synopsis
- - The study investigates how chronic inflammation affects the metabolism of lipoproteins and serum lipid levels in dogs with protein-losing enteropathy (iPLE), comparing them to healthy dogs.
- - Results show that dogs with iPLE have lower levels of certain lipids and proteins, while having higher levels of triglycerides and C-reactive protein (CRP) than healthy dogs.
- - No significant correlations were found between the lipid profiles and disease activity, but some lipoproteins did correlate with CRP and paraoxonase-1 (PON-1) activity, indicating potential links between inflammation and lipid metabolism.
Introduction: Canine protein-losing enteropathy (PLE) is a syndrome characterized by gastrointestinal loss of proteins. While fecal microbiome and metabolome perturbations have been reported in dogs with chronic enteropathy, they have not been widely studied in dogs with PLE. Therefore, the study aims were to investigate gut microbiome and targeted fecal metabolites in dogs with inflammatory PLE (iPLE) and evaluate whether treatment affects these changes at short-term follow-up.
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- * An 8-month-old French Bulldog showed symptoms like chronic cough and diarrhea; testing revealed Strongyloides stercoralis larvae, indicating a parasitic infection that led to enteropathy and bronchopneumonia.
- * Treatment with fenbendazole was initially ineffective, but two doses of ivermectin successfully resolved the dog’s symptoms, and follow-up tests confirmed the absence of the parasite after six months.