Publications by authors named "Fran Benedetti"
Infect Immun
October 2009
Article Synopsis
- CGD patients are at risk for serious infections from Burkholderia cepacia complex; a study compared immune responses to different strains.
- A CGD isolate (CGD1) showed greater cell association and invasion in CGD leukocytes than an environmental isolate (Env1), indicating a stronger ability to infect these patients.
- In mouse models, CGD1 was highly virulent and led to significantly higher bacterial loads and inflammation compared to Env1, highlighting why CGD patients are more vulnerable to certain infections.
