Publications by authors named "Fraile E"

Resilience mechanisms can be dynamically triggered throughout the lifecourse by resilience factors in order to prevent individuals from developing stress-related pathologies such as posttraumatic stress disorder (PTSD). Some interventional studies have suggested that listening to music and musical practice experiencing a traumatic event decrease the intensity of PTSD, but surprisingly, no study to our knowledge has explored musical experience as a potential resilience factor the potential occurrence of a traumatic event. In the present conceptual analysis, we sought to summarize what is known about the concept of resilience and how musical experience could trigger two key mechanisms altered in PTSD: emotion regulation and cognitive control.

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Numerous neuropsychological studies have investigated the effect of music on patients with Alzheimer's disease. Findings suggest that music can improve behavioral symptoms, but its potential effects on cognitive abilities of patients still require more investigation. In this 2 × 2 crossover study, we measured the impact of learning an individualized song on autobiographical memory recall and other cognitive abilities in 12 patients with mild to moderate Alzheimer's disease.

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Lung vessel segmentation has been widely explored by the biomedical image processing community; however, the differentiation of arterial from venous irrigation is still a challenge. Pulmonary artery-vein (AV) segmentation using computed tomography (CT) is growing in importance owing to its undeniable utility in multiple cardiopulmonary pathological states, especially those implying vascular remodelling, allowing the study of both flow systems separately. We present a new framework to approach the separation of tree-like structures using local information and a specifically designed graph-cut methodology that ensures connectivity as well as the spatial and directional consistency of the derived subtrees.

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Background: To determine the level of satisfaction and the sociodemographic characteristics of patients who receive epidural analgesia during labour.

Material And Methods: A SERVQHOS questionnaire administered, with consecutive sampling, to 140 patients who had received an epidural anaesthetic for pain control during labour between January and June 2014, at the Hospital San Pedro.

Results: A total of 140 questionnaires were completed.

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Hypoxia-inducible factor-1α (HIF-1α) and all-trans retinoic acid (ATRA) afford protection in several experimental models of kidney disease. HIF-1α protein is degraded under normoxia but stabilized by hypoxia, which activates its transcription factor function. ATRA activates another set of transcription factors, the retinoic acid receptors (RAR) α, β and γ, which mediate its effects on target genes.

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Objective: To determine the usage of CT in our diagnostic imaging department and the dose of radiation CT delivered to patients.

Material And Methods: We carried out two studies, a retrospective study on the administrative data from one year and a prospective study over one month, to determine the amount of activity of the two multislice CT scanners in our department. We recorded the total number of examinations, the different types of examination performed, and the age distributions of the patients examined.

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The correct staging of the tumors has important consequences in the planning of the treatment in the patients with cancer of larynx, hypopharynx and oropharynx. The objective of this paper is to study the correlation of the clinical, radiologic and pathologic staging with the purpose to evaluate if the computed tomography (CT) is effective in the diagnostic of the stage in the different tumoral findings. We did a retrospective study in 34 patients with pharynx and larynx cancer in the "Hospital Universitario Príncipe de Asturias" between the years 1994-1998.

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The influence of culture medium buffer capacity, the supplementation of culture medium with L-ala and the requirement of calcium for exoprotease production by Antarctic psychrotrophic Stenotrophomonas maltophilia strains ANT-1-1 and ANT-7-1 were examined. When increasing concentrations of calcium chloride (0 to 0.3 g l-1) were added to culture media, maximum protease production yields increased 70-75% (ANT-1-1) and 50% (ANT-7-1), while biomass levels showed little difference.

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The fourth-day extract of a solid-state culture of the mesophilic Mucor sp. (M-105) strain showed a high milk-clotting activity and a clotting/proteolytic activity ratio similar to that of commercial preparations from microbial origin used in cheese manufacture. After ultrafiltration of the crude extract, the milk-clotting proteinase was purified in two steps: ion-exchange followed by size-exclusion chromatography.

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Objective: Magnetic resonance (MR) is considered to be the best method available at present for diagnosis of lesions of the brachial plexus. In this study we analyze our experience in patients with pathology of the brachial plexus.

Material And Methods: Between August 1991 and March 1997 we did magnetic resonance studies on 42 patients with pathology of the brachial plexus.

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The presence of gas in the wall of the stomach in a child is a rare condition and usually indicates necrotising enterocolitis. We report a case of gastric emphysema in a 20-day-old baby girl with duodenal obstruction due to a congenital duodenal diaphragm. This association is extremely rare and has been described only once in the literature.

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Because of the importance of nutrition in the development of bone mass, we studied the nutritional state, and bone state by means of metacarpal radiogrammetric measurements and vertebral morphometry in a group of 40 premenopausal women born between 1960 and 1970, mean age 29 +/- 5 years, and in another group of 40 postmenopausal women born between 1934 and 1944, mean age 55 +/- 4 years. Both groups were considered normal, the main characteristic distinguishing them being that the women born between 1934 and 1944 grew up in a period of widespread malnutrition in Spain and the women born between 1960 and 1970 grew up in a period of normal nutrition. Protein, carbohydrate and fat intake in these two periods differed significantly (p < 0.

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Acid protease production by a local strain of Mucor bacilliformis was performed by solid state cultivation on different agricultural by-products as substrate. The effects of different parameters on enzyme biosynthesis were studied: Wheat bran wetted at 120% with a 200 mM HCl solution and inoculated with 5 x 10(5) spores/g produced a milk clotting activity of 7500 U/g bran after 72 h cultivation at 24 degrees C.

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We evaluated the precision of metacarpal radiogrammetry by computed radiography as a technique for bone mass measurement. Measurements obtained using this method were compared with densitometric measurements of total body bone mass using dual-energy X-ray absorptiometry. Our results showed that the coefficients of variation for radiogrammetric measurements were similar in 60 women with osteoporosis and in 100 normal women: 0.

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Computed radiography was used to make radiogrammetric measurements of the second metacarpal in 240 women, 180 considered normal and 60 osteoporotic. These measurements had a coefficient of variation for the external diameter of 0.74% in normal women and 0.

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We studied the behavior of radiogrammetric and densitometric measurements in relation to season and body weight in a group of 30 healthy premenopausal women. Measurements were made at 6-month intervals, in summer/fall when bone density increases and in winter/spring when bone density declines. Total body bone mineral content (TBBMC) and regional bone mineral content (RBMC) were measured using dual-energy X-ray absorptiometry (DXA).

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An acid protease having milk clotting activity has been isolated from Mucor bacilliformis cultures. The enzyme was basically purified by ionic exchange chromatography. An average yield of 29 mg purified product was obtained from 100 mL crude extract.

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We review our experience with Magnetic Resonance Imaging (MRI) in the evaluation of 6 patients showing anorectal malformation, and 4 more with persistent postoperative fecal incontinence. Preoperative sagittal, axial and coronal planes were studied with special consideration to the pelvic and vertebral structures. The excellent resolution of MRI allowed accurate identification of the pelvic musculature in all patients, including those with bizarre sacral abnormalities.

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The MR images obtained of brain during the process of myelination taking place from birth to 2 years of age are analyzed. Basically, the study focuses on the changes in signal intensity experienced by the elements of the brain in the different sequences, consisting in an increase (T1 weighted sequence) or decrease (T2 sequences) in the signal. The chronological evolution of these changes is compared with the classic myelination pattern, described prior to the development of MR, based on necropsies.

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We have studied the neuroepithelial tumors in childhood, about their epidemiological, clinical and histological aspects, the macroscopic tumoral structure and the findings obtained by magnetic resonance imaging. We stress the differential diagnosis features among the various tumoral types, based on bibliography and our own clinical experience.

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A qualitative and quantitative study of the predominant heterotrophic bacterial flora in the stomach and intestine of the Antarctic fish Notothenia neglecta was carried out: 10 newly caught specimens (Potter cove, King George Island, South Shetland Islands) were analyzed. The cultures were made under aerobic and anaerobic conditions. The stomach flora showed variable results between samples which are probably related to the flora ingested with food.

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The production of L-threonine in submerged culture was studied in the following bacterial strains; Brevibacterium flavum ATCC 21269, Corynebacterium acetoacidophilum ATCC 21270, Escherichia coli ATCC 21149, E. coli NRRL 12098, E. coli NRRL 12099 and E.

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Milk-clotting enzyme from a strain of Mucor varians Pispek selected in a previous work was obtained by solid culture followed by water extraction. Moistened wheat bran (120% water on dry bases) proved to be a good medium for the production of the milk-clotting enzyme. The production may be related to growth and 4,000 U milk-clotting activity by g of wheat bran was achieved.

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