Publications by authors named "Fouzia Moursli"
Pain Physician
January 2013
Article Synopsis
- Dextromethorphan (DM) may be effective as a pre-emptive analgesic, particularly when combined with quinidine, which inhibits CYP2D6 metabolism, thereby increasing DM's effectiveness in managing acute post-operative pain.
- A study involving 40 patients undergoing knee ligament surgery found that those taking quinidine alongside DM needed significantly fewer NSAIDs for pain relief compared to those on a placebo.
- While the results are promising, indicating that CYP2D6 activity impacts DM's analgesic effects, further studies with larger sample sizes are needed to confirm these findings.
