Comparison of outcomes for fixed and weight-based four-factor prothrombin complex concentrate dosing regimens.

Objectives: Although fixed dose regimens using four-factor prothrombin complex concentrate (4F-PCC) are more widely accepted, using a 'one size fits all' approach remains an area of uncertainty. The primary objective of this study was to compare percentages of haemostasis between fixed dose and weight-based dose 4F-PCC regimens for multiple bleed types and anticoagulants. Secondary objectives compared differences in the time to administration and in-hospital mortality.

Performance improvement: getting an early start.

Background: The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) and the Surgical Care Improvement Program (SCIP) can be utilized to develop quality initiatives to improve surgical care. Understanding the fundamentals of quality measures provides insight to the six Accreditation Council on Graduate Medical Education (ACGME) competencies. Resident education needs a robust exposure to quality measures, such as NSQIP and SCIP to prepare surgeons for tomorrow's healthcare system.