Publications by authors named "Fougnot S"
Article Synopsis
- The study aimed to evaluate the effects of selective reporting of antibiotic susceptibility testing (AST) results on reducing inappropriate broad-spectrum antibiotic prescriptions in outpatient care for E. coli infections.
- It involved a comparison of two laboratory groups in France, analyzing data before and after the intervention from 2017 to 2019, with a focus on the rate of antibiotic prescriptions.
- Results indicated that selective reporting significantly reduced the prescription of broad-spectrum antibiotics, especially third-generation cephalosporins, without any negative clinical consequences, although there is still potential for further improvements.
Article Synopsis
- Selective reporting of antibiotic susceptibility testing (AST) is aimed at improving antibiotic stewardship by reducing unnecessary prescriptions.
- The study evaluated the feasibility and acceptability of implementing selective reporting for urine cultures among lab professionals and prescribers, uncovering both facilitators and barriers to its national rollout.
- Results showed that implementing this selective reporting method required approximately 80 hours and €23,000, but it was generally well-received by users, with minimal requests for complete AST reports from general practitioners.
: Selective reporting of antibiotic susceptibility testing (AST) results is a potentially interesting tool for antibiotic stewardship. It consists of performing AST according to usual practices, but the results are reported to the prescriber only for a few antibiotics (i.e.
View Article and Find Full Text PDFIntroduction: Antibiotic resistance is a serious and increasing worldwide threat to global public health. One of antibiotic stewardship programmes' objectives are to reduce inappropriate broad-spectrum antibiotics' prescription. Selective reporting of antibiotic susceptibility test (AST) results, which consists of reporting to prescribers only few (n=5-6) antibiotics, preferring first-line and narrow-spectrum agents, is one possible strategy advised in recommendations.
View Article and Find Full Text PDFObjectives: Although nursing homes are thought to be significant reservoirs of antibiotic-resistant bacteria, very few large population-based studies comparing antibiotic resistance prevalence in nursing homes and in the community have adjusted for patient characteristics. Our objective was to compare the prevalence of antibiotic resistance of Enterobacteriaceae cultured from urine samples of nursing home residents with that of community-dwelling adults, all aged 65 years or older.
Methods: This study analysed around 20 000 positive urine samples sent to a large laboratory in north-eastern France from 2014 to 2017, collected from individuals aged 65 years or older.
Selective reporting of antibiotic susceptibility test (AST) results is a potential intervention for laboratory-based antibiotic stewardship. The aim of this study was to assess the impact of AST reporting on the appropriateness of antibiotics selected by French general practitioners for urinary tract infections (UTIs). A randomised controlled case-vignette study in a region of northeast France surveyed general practitioners between July and October 2015 on treatment of four clinical cases of community-acquired Escherichia coli UTIs (two cases of complicated cystitis, one of acute pyelonephritis and one male UTI).
View Article and Find Full Text PDFObjectives: We sought to assess the importance of extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae in urinary tract infections in outpatients in France.
Methods: Retrospective laboratory based survey analysing susceptibility patterns of Escherichia coli and Klebsiella pneumoniae isolates providing from urines collected from outpatients during three months in 2013.
Results: Four hundred and ninety-nine laboratories collected data on 51,643 E.
Objectives: To evaluate the antibiotic susceptibilities of Propionibacterium acnes isolates from central nervous system (CNS) infections to agents used in current treatment regimens.
Methods: MICs of 16 reference antibiotics were determined by an agar dilution method for 24 consecutive strains of P. acnes isolated from individual patients with intracranial empyema or brain abscess.
Objective: This study was designed to test the accuracy of capillary ketonemia for diagnosis of ketosis after interruption of insulin infusion.
Research Design And Methods: A total of 18 patients with type 1 diabetes treated by external pump were studied during pump stop for 5 h. Plasma and capillary ketonemia and ketonuria were determined every hour from 7:00 A.