Publications by authors named "Fotis Fousekis"
Article Synopsis
- A study compared the effectiveness of tofacitinib and ustekinumab as third-line treatments for patients with moderate to severe ulcerative colitis (UC) who did not respond to earlier therapies (anti-TNF and vedolizumab).
- Out of 117 patients followed for about 11.6 months, 54% experienced disease progression, with ustekinumab being associated with a higher risk of progression compared to tofacitinib.
- While tofacitinib showed better results in preventing disease progression, no major differences were noted in secondary outcomes or adverse events, highlighting the need for more extensive clinical trials to validate these findings.
Intestinal metaplasia of the stomach (IM) is considered a pre-cancerous lesion and is a potential precursor to adenocarcinoma. Metabolic syndrome (MetS) has been associated with lesions to the gastrointestinal tract such as the risk of developing Barett esophagus. Vascular endothelial growth factor and leptin have been associated with either gastrointestinal tract carcinogenesis or MetS.
View Article and Find Full Text PDFGastric cancer (GC) is one of the most common and deadly malignancies worldwide. Helicobacter pylori have been documented as a risk factor for GC. The development of sequencing technology has broadened the knowledge of the gastric microbiome, which is essential in maintaining homeostasis.
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