Publications by authors named "Fotios Michas"

The Framingham Stroke Risk Profile (FSRP) is a novel and reliable tool for estimating the 10-year probability for incident stroke in stroke-free individuals, while the predictive value of ambulatory blood pressure monitoring (ABPM) for first-ever and recurrent stroke has been well established. We sought to evaluate cross-sectionally the association of ABPM parameters with FSRP score in a large sample of 2343 consecutive stroke-free individuals (mean age: 56.0±12.

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In the current study, the authors sought to assess whether the time rate of systolic and diastolic blood pressure variation is associated with advanced subclinical stages of carotid atherosclerosis and plaque echogenicity assessed by gray scale median. The authors recruited 237 consecutive patients with normotension and hypertension who underwent 24-hour ambulatory blood pressure monitoring and carotid artery ultrasonography. There was an independent association between low 24-hour systolic time rate and increased echogenicity of carotid plaques (adjusted odds ratio for highest vs lower tertiles of gray scale median, 0.

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The clinical importance of white-coat hypertension (WCH) remains a controversial issue. The aim of this study was to evaluate the association of isolated systolic, isolated diastolic, and systolic/diastolic WCH with common carotid artery intima-media thickness (CCA-IMT) and to compare each subgroup of WCH against other blood pressure (BP) phenotypes in terms of CCA-IMT values. A total of 1382 consecutive patients underwent 24-hour ambulatory BP monitoring and carotid artery ultrasonographic measurements.

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Objective: Ambulatory blood pressure monitoring provides a unique tool in the evaluation of night-time blood pressure (BP), having a critical role in the detection of a blunted nocturnal fall and of elevated night-time BP. Both nondipping status and nocturnal hypertension are associated with increased cardiovascular risk and target organ damage. The aim of our study was to investigate the impact of both nondipping status and nocturnal hypertension on left ventricular mass (LVM), assessed by means of echocardiography in a consecutive cohort of untreated participants.

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Objectives: The masking effect (ME) is present in masked hypertensive patients; however, both normotensive and hypertensive individuals may show a similar phenomenon. Previous studies have shown that ME has been associated with left ventricular hypertrophy and microalbuminuria in treated hypertensive patients. The aim of our study was to evaluate the association between the magnitude of systolic ME and the extent of common carotid artery intima-media thickness (CCA-IMT) development in normotensive individuals and untreated masked hypertensive and hypertensive patients.

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Masked hypertension (MH) is associated with advanced target organ damage. However, patients with MH constitute a group of individuals with heterogeneous characteristics concerning their ambulatory blood pressure (BP) status. The aim of this study was to evaluate the association of isolated systolic MH, isolated diastolic MH, and systolic/diastolic MH with carotid artery intima-media thickness (CIMT).

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Article Synopsis
  • The study investigated the relationship between blood pressure variability from ambulatory blood pressure monitoring (ABPM) and common carotid artery intima-media thickness (CCA-IMT) in untreated hypertensive patients.
  • Hypertensive individuals showed significantly higher rates of blood pressure variation compared to normotensive participants, with evidence suggesting that this variability is linked to CCA-IMT.
  • Results indicate that short-term beat-to-beat blood pressure variation may be a more accurate predictor of target organ damage than the variability assessed through ABPM.
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Objectives: Both brain edema and increased blood pressure (BP) variability are associated with poor outcome after stroke. The aim of the present study was to evaluate a possible association between edema formation and a relatively new index of BP variability defined as time rate (TR) of BP variation.

Patients And Methods: A total of 128 first-ever acute stroke patients underwent 24-h ambulatory BP monitoring within 24 h from onset of stroke.

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Objectives: Baroreceptor reflex sensitivity (BRS) is an important factor in the homeostatic regulation of the cardiovascular system. Arterial stiffening also provides direct evidence of target organ damage in hypertensive patients. The aim of the present study was to evaluate a possible association between BRS and pulse wave velocity (PWV) in a population of normotensive and hypertensive patients.

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Article Synopsis
  • The study investigates the link between the rate of blood pressure (BP) variation and the severity of coronary artery lesions in normotensive patients suspected of having coronary artery disease.
  • Findings indicate that patients with coronary artery disease showed higher daytime rates of systolic BP variation compared to controls, and this variation is independently associated with the severity of coronary lesions as measured by the Gensini score.
  • The research suggests that greater BP variability may stress arterial walls more significantly, potentially being an important factor in assessing coronary artery disease risk alongside traditional factors like diabetes and smoking.
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Background: Recent studies have reported that prehypertension is associated with increased values of common carotid artery intima-media thickness (CCA-IMT). The aim of this study was to assess the impact of daytime ambulatory blood pressure (BP) levels on the association of prehypertension with CCA intima-media thickening in prehypertensive subjects.

Methods: A total of 807 subjects with office systolic BP<140 and diastolic BP<90mmHg, underwent 24h ambulatory BP (ABP) monitoring and carotid artery ultrasonographic measurements.

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Article Synopsis
  • The study investigated the link between blood pressure (BP) variation and renal function in untreated hypertensive patients using 24-hour ambulatory BP monitoring.
  • A total of 803 patients were classified based on their estimated glomerular filtration rate (eGFR), with those having lower eGFR showing significantly higher rates of systolic BP variation.
  • Results indicate that the 24-hour rate of systolic BP variation is a significant independent factor associated with impaired renal function, suggesting that BP fluctuations should be considered alongside traditional BP measurements when evaluating target-organ damage in hypertensive patients.
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