Publications by authors named "Foteini Athanasopoulou"
Article Synopsis
- The study examines how intratumour heterogeneity (ITH) impacts lung cancer evolution, leading to immune evasion and therapy resistance using data from non-small cell lung cancer patients.
- It analyzes RNA and whole-exome sequencing from 354 tumours, revealing significant transcriptomic diversity that contributes to phenotypic variation and influences the selection process during tumour evolution.
- The research identifies key mechanisms like allele-specific expression and RNA-editing enzyme activity that connect the genome and transcriptome, affecting metastasis potential and the overall evolution of lung cancer.
Nanomedicines are revolutionizing healthcare as recently demonstrated by the Pfizer/BioNTech and Moderna COVID-2019 vaccines, with billions of doses administered worldwide in a safe manner. Nonalcoholic fatty liver disease is the most common noncommunicable chronic liver disease, posing a major growing challenge to global public health. However, due to unmet diagnostic and therapeutic needs, there is great interest in the development of novel translational approaches.
View Article and Find Full Text PDFCoronavirus disease 2019 (COVID-19) is a deadly respiratory disease caused by severe acute respiratory syndrome coronavirus 2, which has caused a global pandemic since early 2020 and severely threatened people's livelihoods and health. Patients with pre-diagnosed conditions admitted to hospital often develop complications leading to mortality due to acute respiratory distress syndrome (ARDS) and associated multiorgan failure and blood clots. ARDS is associated with a cytokine storm.
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