Response Evaluation of Malignant Liver Lesions After TACE/SIRT: Comparison of Manual and Semi-Automatic Measurement of Different Response Criteria in Multislice CT.

 To compare measurement precision and interobserver variability in the evaluation of hepatocellular carcinoma (HCC) and liver metastases in MSCT before and after transarterial local ablative therapies.  Retrospective study of 72 patients with malignant liver lesions (42 metastases; 30 HCCs) before and after therapy (43 SIRT procedures; 29 TACE procedures). Established (LAD; SAD; WHO) and vitality-based parameters (mRECIST; mLAD; mSAD; EASL) were assessed manually and semi-automatically by two readers.

Liver lesion segmentation in MSCT: effect of slice thickness on segmentation quality, measurement precision and interobserver variability.

Purpose: To evaluate the effect of slice thickness on semi-automated liver lesion segmentation.

Materials And Methods: In this retrospective study, liver MSCT scans from 60 patients were reconstructed at a slice thickness of 1.5 mm, 3 mm and 5 mm.