Evaluation of the sperm parameters, oxidative stress, and histopathological effects of vitamin B in preventing -induced testicular toxicity: An experimental study.

Background: () causes sterility by affecting the reproductive system. Vitamin B improves sperm quantity and function.

Objective: Vitamin B protection against adverse effects was investigated.

Evaluation of serum pro/anti-angiogenic biomarkers in hyperglycemic rats treated with seeds, alone and in combination with Glibenclamide.

Introduction: Herbal medicines are commonly used by many people with diabetes in addition to standard treatment. Plants contain numerous known and unknown compounds that may exacerbate or ameliorate diabetes complications. Therefore, it is crucial to be aware of the side effects of these herbs before prescribing them.

Evaluation of novel biomarkers for early diagnosis of bisphenol A-induced coronary artery disease.

Introduction: Bisphenol A (BPA), a ubiquitous synthetic monomer primarily used in the manufacture of polycarbonate plastic and epoxy resins and as a non-polymer additive to other plastics, can leach into the food and water supply and has been linked to cardiovascular disease (CVD). This study aimed to analyze BPA levels in patients with varying numbers of coronary artery stenosis and evaluate the prognostic value of new biomarkers cluster of differentiation 36 (CD36) and heart-type fatty acid-binding protein (H-FABP), compared to troponin I and creatine kinase (CK) MB, for detecting myocardial injury.

Method: Eighty nine patients undergoing angiography at Urmia Hospital from March 2019 to 2020 were included.

MicroRNA-372 acts as a double-edged sword in human cancers.

MicroRNAs (miRNAs or miRs) are non-coding, single-stranded, endogenous RNAs that regulate various biological processes, most notably the pathophysiology of many human malignancies. It process is accomplished by binding to 3'-UTR mRNAs and controlling gene expression at the post-transcriptional level. As an oncogene, miRNAs can either accelerate cancer progression or slow it down as a tumor suppressor.

Screening of potential inhibitors of COVID-19 with repurposing approach via molecular docking.

SARS-CoV-2 (COVID-19) is the causative organism for a pandemic disease with a high rate of infectivity and mortality. In this study, we aimed to assess the affinity between several available small molecule and proteins, including Abl kinase inhibitors, Janus kinase inhibitor, dipeptidyl peptidase 4 inhibitors, RNA-dependent RNA polymerase inhibitors, and Papain-like protease inhibitors, using binding simulation, to test whether they may be effective in inhibiting COVID-19 infection through several mechanisms. The efficiency of inhibitors was evaluated based on docking scores using AutoDock Vina software.

Dual role of microRNA-1297 in the suppression and progression of human malignancies.

MicroRNAs (miRNAs) are endogenous, non-coding, single-stranded and tiny RNAs that modulate several biological functions, more importantly, the pathophysiology of numerous human cancers. They are bound with target mRNAs and thereby regulate gene expression at post-transcriptional levels. MiRNAs can either trigger cancer progression as an oncogene or alleviate it as a tumor suppressor.

Effect of different levels of clove (Syzygium aromaticum L.) essential oil on growth performance and oxidative/nitrosative stress biomarkers in broilers under heat stress.

A 49-day fully randomized trial was conducted to investigate the dietary effects of clove (Syzygium aromaticum L.) essential oil (CEO) on growth performance and oxidative/nitrosative stress biomarkers in broilers under heat stress. A total of 288 male broilers (Ross 308) were randomly divided into 6 dietary groups (4 replicates and 12 birds/replicate) and supplemented as follows: (I) Normal control (NC) received only basal diet under normal condition.

MicroRNA-154: A Novel Candidate for Diagnosis and Therapy of Human Cancers.

MicroRNAs (miRNAs) are endogenous, non-coding, single-stranded, tiny RNAs with 21-23 nucleotides that regulate several biological functions through binding to target mRNAs and modulating gene expression at post-transcriptional levels. Recent studies have described crucial roles for miRNAs in pathophysiology of numerous human cancers. They can act as an oncogene and promote cancer or as a tumor suppressor and alleviate the disease.

Association between the microbiota and women's cancers - Cause or consequences?

Breast, ovarian and uterine cancers are the most common neoplasms among women. Several mechanisms may be involved in oncogenesis and these include environmental and genetic factors. Bacteria may affect the development of some cancers, with bacterial components, their products and metabolites interacting with susceptible tissues.

Genetic polymorphisms and epigenetic regulation of survivin encoding gene, BIRC5, in multiple sclerosis patients.

Background: The persistent the inflammatory condition in multiple sclerosis (MS) may due to the aberrant regulation of the elimination of the pathogenic autoreactive lymphocytes through apoptosis. Survivin, encoded by the BIRC5 gene, has been indicated to be involved in the regulation of apoptosis. This survey intended to investigate the genetic and microRNA mediated regulation of survivin in relapsing-remitting MS (RRMS) disease.