Publications by authors named "Forgues Dominique"

Article Synopsis
  • * Conducted at Montpellier University Hospital, it involved 80 fetuses during third-trimester ultrasounds, confirming a normal vessel position in 96.2% of cases, with perfect agreement between prenatal and neonatal scans for 74 babies.
  • * The findings suggest that prenatal ultrasound is effective for assessing SMA and SMV positions, and for cases of abnormal positioning, further imaging (like MRI) is recommended to check for potential intestinal malrotation.
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Introduction: Gastro-esophageal reflux disease (GERD) is the most frequent long-term morbidity of congenital diaphragmatic hernia (CDH) survivors. Performing a preventive fundoplication during CDH repair remains controversial. This study aimed to: (1) Analyze the variability in practices regarding preventive fundoplication; (2) Identify predictive factors for fundoplication.

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Article Synopsis
  • Smooth Muscle Cells (SMCs) can change their behavior and functionality, switching between a relaxed state and a more active, proliferative state, which can be linked to dysfunction.
  • In a study of infants with chronic intestinal pseudo-obstruction (CIPO), it was found that SMCs had reduced contractile markers and increased levels of a receptor called PDGFRA, indicating a shift towards a less differentiated state.
  • Understanding this phenotypic change in CIPO-SMCs could lead to new therapeutic strategies aimed at encouraging these cells to differentiate properly and improve gut motility.
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Article Synopsis
  • The study examined 4580 fetuses over a nine-year period to explore the clinical spectrum of genital defects diagnosed before birth and identify factors predicting severe phenotypes at birth.
  • A total of 61 cases were analyzed, with a high prenatal diagnosis accuracy of 90.1%, mostly involving undervirilized boys (68.8%) and some virilized girls (11.5%).
  • Key findings indicated that early second trimester detection, intra-uterine growth restriction, and penile curvature were linked to more severe cases, highlighting the importance of prenatal imaging for early intervention.
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Objective: To assess specific, direct, and indirect prenatal ultrasound features in cases of fetal midgut volvulus.

Methods: Retrospective case series of neonatal volvulus, based on postnatal and prenatal imaging findings that occurred from 2006-2017. Prenatal and postnatal signs including the specific "whirlpool sign" were computed.

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Article Synopsis
  • * Out of 5,450 cases of fetal anomalies, only 14 (0.3%) were diagnosed with splenic cysts, typically diagnosed around 30 weeks of gestation; most had a single cyst.
  • * By 6 months post-birth, about 36% of the cysts had completely disappeared, and although some reduced in number, nearly half still persisted without causing any symptoms.
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Introduction: Non-operative management (NOM) of splenic trauma in children is currently the treatment of choice.

Purpose: We report a series of 83 cases in order to compare our results with literature data.

Patients And Methods: For this, we conducted a retrospective study of 13 years and collected 83 cases of children with splenic trauma contusion, managed at Lapeyronie Montpellier Hospital in Visceral Pediatric Surgery Department.

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  • Mesoblastic nephroma is the most common type of fetal tumor in the kidneys, but this report is about a rare case of intrarenal neuroblastoma found before birth.
  • A 30-week-old fetus had an unusual mass in its kidney seen during an ultrasound, and after birth, doctors found the baby had high blood pressure and heart issues.
  • After surgery to remove the tumor, tests showed it was neuroblastoma, and doctors suggest that certain signs like high blood pressure and specific chemicals in urine could help detect such tumors in the future.
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Purpose: This retrospective study reports our experience in laparoscopic approach after failure of antireflux surgery. It evaluates the results and circumstances of failure of the initial procedure to understand indications of refundoplication.

Methods: Four hundred seventeen patients were operated on for a gastroesophageal reflux disease (GERD) by laparoscopy in our unit from August 1993 to February 2005.

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Background: Complex procedures for managing congenital abnormalities are reported to be feasible. However, neonatal videosurgery involves very specific physiologic constraints. This study evaluated the safety and complication rate of videosurgery during the first month of life and sought to determine both the risk factors of perioperative complications and the most recent trends in practice.

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Purpose: The indications for thoracoscopy remain imprecise in cases of pleural empyema. This study aimed to identify preoperative prognostic factors to help in the surgical decision.

Methods: From 1996 to 2004, 50 children with parapneumonic pleural empyema underwent thoracoscopy either as the initial procedure (n = 26) or after failure of medical treatment (n = 24).

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Objectives: Video-surgery in neonates is recent. Data on the respiratory, hemodynamic, and thermic effects during the first month of life are still sparse. This study aimed to evaluate the tolerance of video-surgery in neonates and to determine the risk factors of per-operative complications.

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Introduction: Cavitary necrosis remains a rare complication of bacterial pneumonia in children. Conservative medical treatment and radical surgical treatment with lung resection are the current therapeutic choices. Evaluation of thoracoscopy for this pathology has not yet been reported.

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