Spatial correlation assessment of multiple earthquake intensity measures using physics-based simulated ground motions.

Predictive models for spatial correlation play an effective role in the assessment of seismic risk associated with distributed infrastructure and building portfolios. However, existing models often rely on simplified approaches, assuming isotropy and stationarity. This paper verifies these assumptions by presenting a comprehensive study using a database of 3D physics-based simulated broadband ground motions for Istanbul, generated by the SPEED software.

Evaluation of Relationship between Intrinsic Radiosensitivity (Survival Fraction at 2 Gy) and Gamma-H2AX Test and Apoptosis of Lymphocytes in Breast Cancer Patients.

Background: Radiotherapy is one of the routine treatment strategies for breast cancer (BC) patients. Different responses of the patient to radiation due to different intrinsic radiosensitivity (RS) were induced to the researcher try to introduce a standard assay for the prediction of RS. Clonogenic assay is recognized as a gold standard method in this subject but because of some of its disadvantages, it is needed for alternative assays.

The Effectiveness of Cognitive-Behavioral Therapy Courses in Improving the Emergency Medicine Residents and Interns' Ability to Regulate their Emotions in Threatening or Stressful Events.

Background: Given that the duties of an emergency medicine (EM) specialist are much more complicated than the other health care professionals, inexperience, weakness or inability to make appropriate decisions, and lack of control over their emotions and stress can lead to medical errors. This study aimed at determining the effect of cognitive-behavioral therapy (CBT) of emotion regulation on the EM assistants' and interns' level of satisfaction and cognitive control of anger and stress.

Materials And Methods: In this study, 25 EM residents and interns were trained in the virtual CBT course while 19 ones were not given any training in the control group and Cognitive Emotion Regulation Questionnaire (CERQ) were filled before and after the training intervention.

Nonlinear frequency analysis of porous Bi directional functionally graded beams utilizing reddy shear deformation theory.

The nonlinear frequency response of bi-directional functionally graded porous beams experienced range of various end conditions is investigated in this work. The end conditions which are simply supported, clamped-simply supported, clamped-clamped, and clamped-free are taken by using the Von Karman geometric nonlinearity, Green's tensor and Reddy third-order shear deformation theory. A generalized differential quadrature technique (GDQM) accompanied by direct numerical iterance approach is proposed to solve equations.

Psychometric properties of Persian version of irritable bowel syndrome- behavioral responses questionnaire (IBS-BRQ).

Aim: This study aimed to determine the psychometric properties of Persian version of Irritable Bowel Syndrome-Behavioral Responses Questionnaire (IBS-BRQ).

Background: In addition to somatic symptoms and complaints, patients with irritable bowel syndrome have specific dysfunctional behaviors that lead to disease persistence and functional disturbance.

Methods: Participants included 170 patients with irritable bowel syndrome, who were diagnosed based on ROM-IV criteria and selected from patients referring to the Gastrointestinal Disorders Clinic, as well as 100 persons from the general population in Isfahan in 2020.

Endodontic Management of a Maxillary Central Incisor with two Roots: A Case Report and Literature Review.

Maxillary incisors are typically straightforward cases for root canal therapy. While it is commonly assumed that maxillary central incisors have a single root canal, they may occasionally exhibit variations in their root canal system anatomy. In this report, we present a case of a maxillary central incisor with multiple root canals and provide a review of relevant literature on this anatomical variation.

A two-echelon location routing problem considering sustainability and hybrid open and closed routes under uncertainty.

Location-routing is an extremely important problem in supply chain management. In the location-routing problem, decisions are made about the location of facilities such as distribution centers as well as the set of vehicle routes. Today, organizations seek to reduce the transportation cost by outsourcing leading to a particular kind of transportation problems known as open routing.

Comparison of the Effect of Intravenous Fentanyl with Low-Dose Ketamine on Pain Relief in Patients Taking Methadone and Suffering from Limb Fractures.

Background: Given the significance of pain control in addicted patients and the prominence of not using opioids due to patient's drug dependence, the present study aimed at comparing and evaluating the effect of intravenous fentanyl with low-dose ketamine on pain relief in patients taking methadone and suffering from limb fractures.

Materials And Methods: The present double-blind randomized clinical trial was performed on 100 patients taking methadone and suffering from limb fractures. The patients were divided into two groups receiving 1 μg/kg single dose of fentanyl and 0.

Identifying New Clusterons: Application of TBEV Analyzer 3.0.

Early knowledge about novel emerging viruses and rapid determination of their characteristics are crucial for public health. In this context, development of theoretical approaches to model viral evolution are important. The clusteron approach is a recent bioinformatics tool which analyzes genetic patterns of a specific E protein fragment and provides a hierarchical network structure of the viral population at three levels: subtype, lineage, and clusteron.

Dentine Thickness of Second Mesibuccal Canals in First Maxillary Molars Prepared with Rotary Instruments.

Introduction: The purpose of this study was to evaluate the thickness of the remaining dentine wall in the danger zone of the second mesiobuccal (MB2) canals using cone-beam computed tomography (CBCT) in maxillary first molars following preparation by means of HERO 642 rotary instruments with different tapers.

Methods And Materials: The study samples included twenty-five mesiobuccal roots of maxillary first molars. A two-step method was employed to prepare the MB2 canals applying HERO 642 instruments: using a 0.

Uninvited Guest: Arrival and Dissemination of Omicron Lineage SARS-CoV-2 in St. Petersburg, Russia.

Following its emergence at the end of 2021, the Omicron SARS-CoV-2 variant rapidly spread around the world and became a dominant variant of concern (VOC). The appearance of the new strain provoked a new pandemic wave with record incidence rates. Here, we analyze the dissemination dynamics of Omicron strains in Saint Petersburg, Russia's second largest city.

Cost-effectiveness of direct oral anticoagulants compared to low-molecular-weight-heparins for treatment of cancer associated venous thromboembolism in Spain.

Aim: Recent studies have compared the efficacy and safety of direct-acting oral anticoagulants (DOAC) and low-molecular-weight heparin (LMWH) for cancer-associated venous thromboembolism (VTE). However, there is no available cost-effectiveness analysis comparing DOAC and LMWH. The study aimed to conduct a cost-effectiveness analysis of DOAC (apixaban, edoxaban, and rivaroxaban) LMWH for the treatment of cancer-associated VTE in Spain from the Spanish healthcare system perspective.

PaCO-EtCO Gradient and D-dimer in the Diagnosis of Suspected Pulmonary Embolism.

Background: The diagnosis of pulmonary embolism (PE) because of nonspecific clinical presentation remains as a challenge for emergency physicians. Arterial to end-tidal partial pressure of carbon dioxide (P(a-Et) CO) gradient may be useful in the evaluation of PE. This aimed to define the diagnostic role of P(a-Et)CO gradient by sidestream capnography, as a noninvasive method, and D-dimer in patients with PE.

Intravenous Thrombolysis by Telestroke in the 3- to 4.5-h Time Window.

While intravenous thrombolysis (IVT) in ischemic stroke can be safely applied in telestroke networks within 3 h from symptom onset, there is a lack of evidence for safety in the expanded 3- to 4. 5-h time window. We assessed the safety and short-term efficacy of IVT in acute ischemic stroke (AIS) in the expanded time window delivered through a hub-and-spoke telestroke network.

Assessment of Thyroid Lobe Dose in Breast Cancer Intraoperative Radiotherapy.

Background: Breast cancer is the most common cancer among women. Considering the fact that a high dose is delivered in a single fraction of IORT, the evaluation of the dose at sensitive organs like thyroid is necessary.

Objective: The current study has aimed to evaluate the received dose to thyroid lobes in the breast IORT technique.

Lymphoscintigraphy in the Time of COVID-19: Effect of Molybdenum-99 Shortage on Feasibility of Sentinel Node Mapping.

In the current study, we reported our experience on sentinel node mapping of breast cancer patients during the extreme shortage of Mo99-Tc99m generators using Tc-99m phytate. During the period from March 7, 2019, to April 18, 2020, due to disruption of molybdenum supply chain, we used low specific activity Tc-99m pertechnetate elute (0.5-2 mCi of TcO in 5 mL) for each kit preparation.

Convolutional Neural Network Based Approach to in Silico Non-Anticipating Prediction of Antigenic Distance for Influenza Virus.

Evaluation of the antigenic similarity degree between the strains of the influenza virus is highly important for vaccine production. The conventional method used to measure such a degree is related to performing the immunological assays of hemagglutinin inhibition. Namely, the antigenic distance between two strains is calculated on the basis of HI assays.

Endotracheal intubation training to medical practitioners: Comparison of the modified 4-step Payton's training method and Halsted's training method in a simulated environment.

Introduction: The ability of physicians to perform endotracheal intubation by laryngoscope is one of the essential skills. The purpose of this study was to evaluate the effectiveness of the four-step python training method with the Halsted's "See one, Do one, and Teach one" training method in endotracheal intubation competency in simulated environment.

Materials And Methods: This quasi-experimental study was performed on two independent groups with posttest.

Evaluation of Dentin Adaptability of Fluoride Varnish as a Root Canal Sealer Using Scanning Electron Microscopy.

Objectives: This study aimed to assess the dentin adaptability of a certain type of fluoride varnish, as a novel root canal sealer, in comparison with AH-Plus sealer.

Materials And Methods: Twenty-four extracted single-rooted, single-canal human permanent teeth with straight and fully formed roots and no internal calcification, resorption or cracks, were selected and decoronated such that the remaining root length was 14 mm in all teeth. Root canals were prepared using the Mtwo rotary file system according to the manufacturer's instructions and filled with gutta-percha and either AH-Plus (n=12) or fluoride varnish (n=12) via the lateral compaction technique.

Novel Biomarkers Aim at Detecting Metastatic Sentinel Lymph Nodes in Breast Cancer.

Background: Intra-operative molecular diagnostic assays are currently used for the detection of lymph node metastases. The objective of this study was to find new biomarkers to improve diagnostic accuracy in the detection of metastatic axillary lymph nodes in breast cancer patients.

Methods: We applied an absolute quantitative real-time reverse transcription-PCR to quantitate the expression of CK19, KLK11, and CLEC3A mRNAs in 79 FFPE sentinel lymph nodes (SLNs) from 35 breast cancer patients.

Does the Winter or Pell and Gregory Classification System Indicate the Apical Position of Impacted Mandibular Third Molars?

Purpose: The present study investigated the relationship of impacted mandibular third molars to the cortical plates and inferior alveolar canal (IAC) using cone-beam computed tomography (CBCT).

Materials And Methods: The present study included CBCT images of 386 lower third molars in 226 patients, for whom the initial panoramic radiographs had revealed a close relationship between the third molars and IAC. The coronal images were prepared to determine the position of apex about the buccal and lingual cortexes and IAC.

Influence of red mud on mechanical and durability performance of self-compacting concrete.

Red mud is a hazardous waste material produced during alkaline leaching of bauxite in the Bayer process. This study proposed the use of red mud to replace fly ash in self-compacting concrete (SCC) and the influences of red mud on fresh and hardened properties, and durability performances of SCC were studied. The fresh concrete results show that red mud had a slight negative impact on the fresh properties of SCC.

Measurement of the serum levels of serum troponins I and T, albumin and C-Reactive protein in chronic hemodialysis patients and their relationship with left ventricular hypertrophy and heart failure.

Background: Hemodialysis patients are at high risk for cardiovascular diseases. The prognostic value of cardiac troponins, albumin and CRP in hemodialysis patients and their association with cardiac diseases has been proven. The aim of this study was to investigate the relationship between these factors and heart failure and left ventricular hypertrophy in hemodialysis patients in Sanandaj city.

The Effectiveness of Sonic-Activated Irrigation in Reducing Intratubular .

Introduction: The purpose of this study was to compare the effectiveness of sonic activation and syringe irrigation of 5.25% sodium hypochlorite in removing the ( ) biofilm.

Methods And Materials: Root canals of 54 extracted human single-rooted central incisors were prepared with ProTaper S1-S2-F1-F2 and Gates Gliden burs size 1, and 2 at the working length.