Publication of articles in international scientific journals has been one of the main strategies for the communication of scientific findings and ideas. Prepublication peer review is a fundamental aspect of the publishing process in indexed scientific journals and, associated with the large growth in journals and articles, there has been a recent challenge in having adequate peer reviewers for international journals. In this article, we provide a short overview of the publishing process, give recommendations to early career researchers about writing peer reviews of adequate quality, and discuss some possibilities for the future.
View Article and Find Full Text PDFThis chapter overviews genetic techniques' fundamentals and methodological features, including different approaches, analyses, and applications that have contributed to advancing health and disease. The aim is to describe laboratory methodologies and analyses employed to understand the genetic landscape of different biological contexts, from conventional techniques to cutting-edge technologies. Besides describing detailed aspects of the polymerase chain reaction (PCR) and derived types as one of the principles for many novel techniques, we also discuss microarray analysis, next-generation sequencing, and genome editing technologies such as transcription activator-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) systems.
View Article and Find Full Text PDFPhilos Trans R Soc Lond B Biol Sci
June 2024
Am J Med Genet B Neuropsychiatr Genet
June 2024
Though the phylogenetic signal of loci on sex chromosomes can differ from those on autosomes, chromosomal-level genome assemblies for nonvertebrates are still relatively scarce and conservation of chromosomal gene content across deep phylogenetic scales has therefore remained largely unexplored. We here assemble a uniquely large and diverse set of samples (17 anchored hybrid enrichment, 24 RNA-seq, and 70 whole-genome sequencing samples of variable depth) for the medically important assassin bugs (Reduvioidea). We assess the performance of genes based on multiple features (e.
View Article and Find Full Text PDFMalignant pleural mesothelioma (MPM) is a rare and aggressive neoplasm of the pleural tissue that lines the lungs and is mainly associated with long latency from asbestos exposure. This tumor has no effective therapeutic opportunities nowadays and has a very low five-year survival rate. In this sense, identifying molecular events that trigger the development and progression of this tumor is highly important to establish new and potentially effective treatments.
View Article and Find Full Text PDFSocial cognition impairments may be associated with poor functional outcomes, symptoms, and disability in social anxiety disorder (SAD) and generalized anxiety disorder (GAD). This meta-analysis aims to determine if emotion recognition and theory of mind (ToM) are impaired in SAD or GAD compared to healthy controls. A systematic review was conducted in electronic databases (PubMed, PsycNet, and Web of Science) to retrieve studies assessing emotion recognition and/or ToM in patients with SAD or GAD, compared to healthy controls, up to March 2022.
View Article and Find Full Text PDFIn recent decades, advances in methods in molecular biology and genetics have revolutionized multiple areas of the life and health sciences. However, there remains a global need for the development of more refined and effective methods across these fields of research. In this current Collection, we aim to showcase articles presenting novel molecular biology and genetics techniques developed by scientists from around the world.
View Article and Find Full Text PDFThe paper presents a framework to emulate spacecraft orbits using GNSS hardware in the loop that enables the evaluation of new orbital positioning algorithms. The framework software generates the spacecraft orbit and the GNSS signals, including the most common perturbations. These signals are modulated and transmitted by a software-defined radio and received by a commercial GPS receiver.
View Article and Find Full Text PDFUnlabelled: Introducción. El síndrome respiratorio agudo grave causado por el nuevo coronavirus SARSCoV-2 es causa de la emergencia sanitaria por la pandemia de COVID-19. Si bien el humano es el el principal huésped vulnerable, en estudios experimentales y reportes de infección natural, se han encontrado casos de zoonosis inversa de SARS-CoV-2 en animales.
View Article and Find Full Text PDFEur Phys J C Part Fields
July 2022
DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE Dual Phase (DP) is a 6 6 6 m liquid argon time-projection-chamber (LArTPC) that recorded cosmic-muon data at the CERN Neutrino Platform in 2019-2020 as a prototype of the DUNE Far Detector. Charged particles propagating through the LArTPC produce ionization and scintillation light.
View Article and Find Full Text PDFPosttraumatic stress disorder (PTSD) is a chronic and multifactorial disorder with a prevalence ranging between 6-10% in the general population and ~35% in individuals with high lifetime trauma exposure. Growing evidence indicates that the immune system may contribute to the etiology of PTSD, suggesting the inflammatory dysregulation as a hallmark feature of PTSD. However, the potential interplay between the central and peripheral immune system, as well as the biological mechanisms underlying this dysregulation remain poorly understood.
View Article and Find Full Text PDFEnvironmental conditions are crucial for crops' growth, development, and productivity. One of the most important physiological factors associated with the production of crops is the use of solar radiation for the photosynthesis process, which determines the amount of assimilates available for crop growth and yield. Three age classes (4, 6, and 14 years) and three planting densities (143, 128, and 115 palms ha) were evaluated in a commercial interspecific x hybrid Coari x La Mé.
View Article and Find Full Text PDFA checklist of 5 subfamilies, 108 genera, and 246 species of stinks bugs (Hemiptera, Pentatomidae) from Colombia is provided. Three genera [Andrallus Bergroth, Placocoris Mayr, and Pseudobebaeus Distant], and eight species [Arocera spectabilis (Drury), Andrallus spinidens (Fabricius), Banasa excavata Thomas, Banasa saileri Thomas, Banasa varians Stl, Chinavia scutellata (Distant), Pelidnocoris haglundi Ruckes, and Pseudobebaeus truncatus (Fallou)] are recorded for the first time from Colombia. Images of dorsal external habitus for all genera that occur in Colombia are offered.
View Article and Find Full Text PDFThe immune function is closely related to iron (Fe) homeostasis and allostasis. The aim of this bioinformatics-assisted review was twofold; (i) to update the current knowledge of Fe metabolism and its relationship to the immune system, and (ii) to perform a prediction analysis of regulatory network hubs that might serve as potential biomarkers during stress-induced immunosuppression. Several literature and bioinformatics databases/repositories were utilized to review Fe metabolism and complement the molecular description of prioritized proteins.
View Article and Find Full Text PDFVolatile compounds that impact the acceptability of strawberry preserves were investigated by untargeted GC-MS flavoromics analysis. Chemical profiles for fifteen strawberry preserves were modeled against consumer liking scores by orthogonal partial least squares (OPLS) with good fit (RY = 0.998) and predictive ability (Q = 0.
View Article and Find Full Text PDFNon-volatile compounds that impact the acceptability of strawberry preserves were investigated by untargeted LC-MS flavoromics analysis. Chemical profiles for fifteen strawberry preserves were modeled against consumer liking scores by orthogonal partial least squares (OPLS) with good fit (RY = 0.995) and predictive ability (Q = 0.
View Article and Find Full Text PDFThe New World genus Castolus Stl, 1858 (Hemiptera: Heteroptera: Reduviidae) contains 16 described species. Based on material from northern Colombia we describe Castolus rafaeli sp. nov.
View Article and Find Full Text PDFThere has been an important global interest in Open Science, which include open data and methods, in addition to open access publications. It has been proposed that public availability of raw data increases the value and the possibility of confirmation of scientific findings, in addition to the potential of reducing research waste. Availability of raw data in open repositories facilitates the adequate development of meta-analysis and the cumulative evaluation of evidence for specific topics.
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