Tailoring the oxidation of benzyl alcohol and its derivatives with (photo)electrocatalysis.

The electrochemical oxidation of alcohol molecules has gained significance as a key anode reaction, offering an alternative to the oxygen evolution reaction (OER) for hydrogen (H) production and carbon dioxide (CO) reduction. The (photo)electrochemical oxidation of benzyl alcohol and its derivatives serves as an important model system, not only because benzyl alcohol oxidation is a critical industrial process, but also because it offers valuable insights into electrocatalytic biomass conversion. Tailoring this reaction through electrochemical and photoelectrochemical methods using heterogeneous noble and transition metal electrocatalysts presents a green approach and the potential for uncovering new reaction mechanisms.

Interfacial Properties of Gold and Cobalt Oxyhydroxide in Plasmon-Mediated Oxygen Evolution Reaction.

Water electrolysis is a green method of storing electrical energy in the chemical bonds of high-energy hydrogen gas (H). However, the anodic oxygen evolution reaction (OER) requires a significant kinetic overpotential, limiting the electrolysis rate. Recently, plasmonic gold nanoparticles (Au NPs) have been introduced to improve charge transfer at the interface between the OER electrocatalysts and the electrolyte under light illumination.

Hepatopulmonary syndrome from liver disease associated with autosomal recessive polycystic kidney disease.

Hepatopulmonary syndrome (HPS) is a life-threatening complication of chronic liver disease (CLD) that currently can be managed only by liver transplant. Though uncommon, some children with kidney disease have coexistent CLD and hence are at risk of developing HPS. Paediatric cases of HPS are rarely described in the nephrology literature.

Covered Stent Correction for Sinus Venosus Atrial Septal Defects, an Emerging Alternative to Surgical Repair: Results of an International Registry.

Background: Covered stent correction for a sinus venosus atrial septal defect (SVASD) was first performed in 2009. This innovative approach was initially viewed as experimental and was reserved for highly selected patients with unusual anatomic variants. In 2016, increasing numbers of procedures began to be performed, and in several centers, it is now offered as a standard of care option alongside surgical repair.

A Multimethod International Mapping Exercise of Arts Interventions in Renal Units: The PAINT Project.

Introduction: Due to the chronic nature of kidney disease, the challenges of symptom burden, and reduced mortality and comorbidity, individuals living with the condition experience substantial anxiety and depression. Incorporating the arts into clinical practice is encouraged to promote and support mental health and well-being. The aim of the PAINT project was to undertake an international mapping exercise to identify the current provision of arts programmes in kidney centres for people living with kidney disease.

Correction: Impacts of trace level chromium on formation of superoxide within uranyl triperoxide complexes.

Correction for 'Impacts of trace level chromium on formation of superoxide within uranyl triperoxide complexes' by Sarah K. Scherrer , , 2024, , 10584-10587, https://doi.org/10.

Structural Integrities of Symmetric and Unsymmetric -Bis-pyridyl Ethylene Powders Exposed to Gamma Radiation: Packing and Electronic Considerations Assisted by Electron Diffraction.

Radiation detection (dosimetry) most commonly uses scintillating materials in a wide array of fields, ranging from energy to medicine. Scintillators must be able to not only fluoresce owing to the presence of a suitable chromophore but also withstand damage from radiation over prolonged periods of time. While it is inevitable that radiation will cause damage to the physical and chemical properties of materials, there is limited understanding of features within solid-state scintillators that afford increased structural integrity upon exposure to gamma (γ) radiation.

Acceptability testing of the Carers-ID intervention to support the mental health of family carers of people with profound and multiple intellectual disabilities.

Background: Providing care and support for a person with intellectual disabilities can be challenging and may negatively impact on family carers' health and wellbeing. A online support programme was co-designed with charitable organisations and family carers, to help meet the mental health and wellbeing needs of family carers.

Objective: To test the acceptability of a newly developed online support programme for carers of people with profound and multiple intellectual disabilities.

Effectiveness of interventions for informal caregivers of people with end-stage chronic illness: a systematic review.

Background: People living with advanced, non-malignant chronic conditions often have extensive and complex care needs. Informal or family caregivers often provide the care and support needed by those with advanced chronic conditions at home. These informal caregivers experience many challenges associated with their caring role, which can impact their own wellbeing.

Probing the protonation and reduction of heptavalent neptunium with computational guidance.

Influence of pH on the speciation and stability of heptavalent neptunium is poorly understood although it is frequently invoked in the literature to explain experimental observations. The present study employs Density Functional Theory (DFT) methodology to assess the thermodynamic feasibility of protonation reactions for the Np(VII) anion complex and the impact on its reduction to Np(VI). This theoretical framework is then explored experimentally through the titration and systematic protonation of Np(VII) in solution and solid-state samples while monitoring them spectroscopically.

CCN4 (WISP-1) reduces apoptosis and atherosclerotic plaque burden in an ApoE mouse model.

Background And Aims: CCN4/WISP-1 regulates various cell behaviours that contribute to atherosclerosis progression, including cell adhesion, migration, proliferation and survival. We therefore hypothesised that CCN4 regulates the development and progression of atherosclerotic plaques.

Methods: We used a high fat fed ApoE mouse model to study atherosclerotic plaque progression in the brachiocephalic artery and aortic root.

Impacts of trace level chromium on formation of superoxide within uranyl triperoxide complexes.

U(VI) peroxides are important within the nuclear fuel cycle, but reactive oxygen species (ROS) can form upon oxidation. Herein, we identified the spectral signatures of a U(VI) diperoxosuperoxide complex (KUPS-1) and observed that the transformation of U(VI) triperoxide (KUT-1) to superoxide forms occurred with trace-level Cr. U(VI) superoxide complexes were identified in EPR solution spectra without the use of spin-traps.

In-Line Thermal Desorption and Dielectric Barrier Discharge Ionization for Rapid Mass Spectrometry Detection of Explosives.

Thermal desorption (TD) of wipe-based samples was coupled with an in-line dielectric barrier discharge ionization (DBDI) source and rugged compact time-of-flight mass spectrometer (MS) for the detection of explosives, propellants, and postblast debris. The chromatography-free TD-DBDI-MS platform enabled rapid and sensitive detection of organic nitramine, nitrate ester, and nitroaromatic explosives as well as black powder and black powder substitute propellants. Parametric investigations characterized the response to TD temperature and optimized DBDI voltage, aerodynamically assisted entrainment, and fragmentation through in-source collision induced dissociation (isCID).

An Expert Delphi Consensus on Risk Factors for Adverse Events After Endovascular Aortic Aneurysm Repair: Tier 1 Study From the International RIsk Stratification in EVAR (IRIS-EVAR) Working Group.

Purpose: Tier 1 of the International RIsk Stratification in EndoVascular Aneurysm Repair (IRIS-EVAR) project aimed to identify important risk factors for adverse events following endovascular aneurysm repair (EVAR).

Materials And Methods: Initially, the steering committee proposed a number of risk factors for adverse events following EVAR. A Delphi consensus was performed as expert panelists were presented with risk factors and provided the opportunity to propose additional risk factors during the process.

Effectiveness of Online Programmes for Family Carers of People with Intellectual Disabilities: Systematic Review of the International Evidence Base.

This systematic literature review examines the evidence base on the effectiveness of online programmes on the mental health and well-being of family carers of people with intellectual disabilities. Databases (ERIC, Medline, PsycINFO and CINAHL) were searched for intervention studies that considered online interventions for family carers of people with intellectual disabilities. Data were extracted using standardised data extraction tools.

Off-the-shelf thermosalience of anthracene-9-thiocarboxamide.

We demonstrate thermosalient behavior in anthracene-9-thiocarboxamide. Upon cooling, the crystalline material spontaneously fractures and jumps. Strong anisotropic thermal expansion precedes thermosalience, and the combination of hydrogen bonds and weaker interlayer interactions affords the macroscopic response.

The role of sealants for achieving anastomotic hemostasis in vascular surgery.

Background: During vascular interventions, connections that link arteries, veins, or synthetic grafts, which are known as an 'anastomosis', may be necessary. Vascular anastomoses can bleed from the needle holes that result from the creation of the anastomoses. Various surgical options are available for achieving hemostasis, or the stopping of bleeding, including the application of sealants directly onto the bleeding vessels or tissues.

Percutaneous Balloon-Expandable Stent Implantation to Treat Transverse Aortic Arch Obstruction: Medium- to Long-Term Outcomes of a Retrospective Multicenter Study.

Background: Transverse aortic arch obstruction is a challenging lesion for which stent implantation provides a potentially important alternate therapy. The objectives were to evaluate the technical, procedural, and medium-to-long-term clinical outcomes of percutaneous stent implantation of transverse aortic arch obstruction.

Methods: This is a retrospective, multicenter study of transverse aortic arch stent implantation.

Quality by Design Considerations for Drop-on-Demand Point-of-Care Pharmaceutical Manufacturing of Precision Medicine.

Distributed and point-of-care (POC) manufacturing facilities enable an agile pharmaceutical production paradigm that can respond to localized needs, providing personalized and precision medicine. These capabilities are critical for narrow therapeutic index drugs and pediatric or geriatric dosing, among other specialized needs. Advanced additive manufacturing, three-dimensional (3D) printing, and drop-on-demand (DoD) dispensing technologies have begun to expand into pharmaceutical production.

Ravulizumab facilitates reduced burden of vascular access, a major benefit in paediatric atypical haemolytic uraemic syndrome.

Background: Atypical haemolytic uraemic syndrome (aHUS) is a rare thrombotic microangiopathy resulting from dysregulation of the alternative complement pathway, leading to multi-organ dysfunction and chronic kidney disease. Eculizumab is an anti-C5 monoclonal antibody therapy that has significantly improved aHUS disease control and patient outcomes, however it requires fortnightly intravenous dosing. This often necessitates long term central access and a high hospital attendance burden.

Radiation-Induced Defects in Uranyl Trinitrate Solids.

Actinides are inherently radioactive; thus, ionizing radiation is emitted by these elements can have profound effects on its surrounding chemical environment through the formation of free radical species. While previous work has noted that the presence of free radicals in the system impacts the redox state of the actinides, there is little atomistic understanding of how these metal cations interact with free radicals. Herein, we explore the effects of radiation (UV and γ) on three U(VI) trinitrate complexes, M[UO(NO)] (where M=K, Rb, Cs), and their respective nitrate salts in the solid state via electron paramagnetic resonance (EPR) and Raman spectroscopy paired with Density Functional Theory (DFT) methods.