Intrauterine diagnosis of heterotaxy syndrome.

Background: Heterotaxy syndrome, including right isomerism and left isomerism, is characterized by an abnormal symmetry of the viscera and veins and is frequently associated with complex cardiac anomalies. We sought to define the feasibility of in utero diagnosis and the postnatal outcome.

Methods: Patients with heterotaxy syndrome were identified from 579 fetal echocardiograms performed from January 1994 to December 1998.