Publications by authors named "Fomin D"

Article Synopsis
  • Alcohol-related deaths in Lithuania decreased by nearly one-third over the past decade but have increased since 2019, with a study analyzing 1,200 autopsies from 2018 to 2022 uncovering rising trends.
  • The main causes of death identified were diseases (54.17%), accidents (31.25%), suicides (12.08%), and homicides (2.5%), with toxicology tests finding a significant link between higher blood alcohol concentrations and victims of accidents.
  • The research highlights the role of alcohol intoxication in fatalities, emphasizing its impact on deaths from accidents and homicides, while also revealing differences in intoxication levels between genders.
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We present successful treatment of a patient with tubular colonic duplication complicated by fecal impaction, perforation and fecal peritonitis. This anomaly is usually detected in children younger 2 years old. In adulthood, this diagnosis is of a precedent-setting nature.

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Soil microbial and enzyme activities are closely related to the spatial variability of soil environmental conditions at the microscale (μm-mm). The origin and localization of the enzymes are somewhat neglected when the measured activity is used to evaluate specific soil functions. The activity of four hydrolytic enzymes (-glucosidase, Cellobiohydrolase, Chitinase, Xylanase) and microbial diversity based on community-level physiological profiling were determined in samples of arable and native Phaeozems with increasing physical impact to soil solids.

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  • The study investigated the connection between alcohol use and sudden cardiac death in patients with coronary artery disease (CAD) at a forensic service in Vilnius, analyzing autopsy protocols over five years.
  • Approximately 33% of the 2133 selected cases of coronary heart disease (CHD) showed evidence of alcohol consumption, with a higher prevalence found in younger males compared to females.
  • Alcohol was found more frequently in the winter and during holidays, and most alcohol-positive deaths occurred during the elimination phase with less severe coronary artery stenosis.
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Obstructive sleep apnea is a disorder characterized by complete or incomplete and recurrent upper airway collapse induced by sleep. Several diagnostic methods for obstructive sleep apnea are used, but only sleep endoscopy allows an endoscopic assessment of pharyngeal collapse during sedation. It is essential to carry out sleep endoscopy following a systematic institutional protocol, in preestablished stages, to ensure better reproducibility and reliability of the results found.

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Reticulate acropigmentation of Kitamura (RAPK) is a rare genetic hyperpigmentation disorder that is a member of the dyschromatoses characterized by hyperpigmented macules or papules that may interrupt the dermatoglyphics with extra-dermatological manifestations. We present a case of a 29-year-old black male who presented with hyperpigmented atrophic macules both on the extremities and genitals, as well as bilateral clinodactyly of the 5th fingers and inferior gingival hyperplasia with teeth crowding, to draw attention to the novel extra dermatological manifestations of RAPK and the differential diagnosis of cutaneous hyperpigmented lesions.

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Follicular helper T lymphocytes are a subpopulation of CD4+ T lymphocytes initially identified in germinal centers of follicles found in secondary lymphoid organs. The primary function of follicular helper T lymphocytes is to help B lymphocytes' antibody production. Changing of antibody class and affinity, B cell differentiation and memory generation depend on cooperation between follicular helper T lymphocytes and B cells.

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: Radioiodine ablation is a frequent procedure for the management of thyroid cancer. In several cases, this treatment is followed by secondary acquired nasolacrimal duct obstruction (SALDO). Risk factors for the development of SALDO are not defined yet.

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Objective: To determine an optimal approach in the treatment of patients with intestinal fistulae.

Material And Methods: We have used the above-mentioned algorithm in the treatment of 46 patients. The majority of patients (=44, 96%) were transferred under supervision of our multidisciplinary team with severe water-electrolyte disturbances and signs of secondary protein-energy malnutrition (PEM) that required complex combined nutritional support.

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Objective: To identify the most important high risk criteria for predicting course of disease, as well as optimal preoperative preparation and surgical strategy in patients with secondary peritonitis.

Material And Methods: A prospective study enrolled 43 patients with diffuse secondary peritonitis.

Results: Significant predictors were Charlson's comorbidity index (=0.

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Erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis are immune-mediated epidermal conditions with variable clinical presentations. Although their clinical presentations often overlap, they have distinct etiologies and potential outcomes, which necessitate specific management strategies. This case is presented to highlight the subtle differences and review management given that Stevens-Johnson syndrome/toxic epidermal necrolysis can rapidly become life-threatening.

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The ketogenic diet has been therapeutically employed from antiquity and is still utilized today in many disease states. With the boom of the complementary and alternative health movement over the last 2 decades, the lay population has grown more interested in disease prevention and treatment via dietary and lifestyle changes and enhancing health and human performance. The ketogenic diet, whether exclusive or intermittent, has been purported by health care professionals and laypersons alike to meet these demands.

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Article Synopsis
  • Discrepancies between clinical diagnoses and autopsies range from 30% to 37%, highlighting the continued importance of deontological examinations, especially in evaluating diagnostic errors.
  • An analysis of 1007 cases from 1989 to 2016 showed that 79% of autopsy diagnoses matched clinical ones, while 13% did not, with the majority of discrepancies involving improperly diagnosed intracranial injuries.
  • The increasing number of these examinations underscores their role in improving healthcare quality and preventing medical mistakes.
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Spleen is typically injured in blunt abdominal trauma. Spleen injuries make 42% of all blunt abdominal injuries. The aim of this study was to perform a retrospective assessment of the cases of acute and subacute isolated traumatic spleen ruptures.

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  • A study analyzed 2000 intentional homicide cases in Vilnius, Lithuania, from 2004 to 2016 to understand the characteristics of victims and methods of death.
  • Children represented only 4.2% of homicide victims, with a majority of victims being male (73%), and female victims generally murdered with a wider variety of objects.
  • The study highlights that Lithuania has a lower rate of gun-related homicides (5.6%) compared to the European average (13%) due to less firearm ownership, and it provides critical data for improving homicide investigation strategies.
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  • Carfentanyl is a highly potent synthetic opioid primarily used in veterinary medicine, but recent cases have shown its dangerous effect on humans, leading to significant poisoning events.
  • Fifteen cases of drug overdose deaths linked to carfentanyl were analyzed, with varied testing methods employed for accurate detection in blood and urine.
  • Symptoms of carfentanyl exposure are similar to those of other opioids, emphasizing the critical need for awareness in forensic medicine due to its potential lethality without proper treatment.
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Article Synopsis
  • Subdural hemorrhage is linked to mechanical brain injuries and has a high death rate, with symptoms that can rapidly develop or remain hidden initially.
  • A study of 110 cases from the State Forensic Medicine Service in Lithuania revealed that higher levels of blood alcohol (mean 2.22 ± 1.3%) corresponded to a lower amount of blood under the dura (mean 81.6 ± 60.5 g) necessary for death in sudden cases.
  • Hospitalized patients showed lower blood alcohol levels (mean 1.33 ± 1%) and larger amounts of blood under the dura (mean 135.6 ± 82.9 g), indicating that even minimal blood accumulation
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Rationale: Positional asphyxia is a rare cause of sudden death and a difficult diagnosis, based mostly on the circumstances of the incident, along with particular external and internal findings, frequent in asphyxia (signs of sudden death).

Patient Concerns: In this report, we are describing one case of adult who was found positioned in a way that led to eventual asphyxiation.

Diagnoses: The final diagnosis of positional asphyxia was determined after the autopsy.

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The article presents 3 forensic medicine cases in the field of electric injury. In addition to traditional findings in electric injury (electric mark and histological findings), the forensic medicine experts in Lithuania also perform an atomic absorption spectrometry analysis. This method confirms the effects of electric current to the body through the electric conductor.

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The ketogenic diet has been shown to be beneficial for numerous diseases across different organ systems, but a dearth of information exists regarding these benefits for skin disease. Here, we searched the literature for known mechanisms behind inflammation in dermatologic disease and correlated that with suggested mechanisms of anti-inflammatory activity of ketones and a ketogenic state in the human body to observe how ketones and ketosis might aid in the treatment of inflammatory skin diseases based on these mechanisms. Specifically, we found that ketones modulate the NRPL3 inflammasome, augment anti-oxidation against reactive oxygen species through various direct and indirect means, and may influence mTOR activity, which are all involved in inflammatory dermatologic diseases to an extent.

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Article Synopsis
  • Hepatodiaphragmatic interposition of the colon is a rare and often asymptomatic condition that is usually discovered incidentally through imaging.
  • Most cases are benign, but when symptomatic, they can lead to complications known as Chilaiditi syndrome, for which conservative treatment is typically provided.
  • This report highlights severe outcomes associated with the anomaly, including megacolon and heart failure, emphasizing the need for proper diagnosis and management to improve patient outcomes.
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