Publications by authors named "Foll-Alnada A F Abdelrahman"
Article Synopsis
- Gold nanoparticles (GNPs) have promising properties for biomedicine but can be toxic to cardiac tissues, with the 10 nm size being the most harmful compared to larger sizes (20 and 50 nm).
- Quercetin (Qur), a natural flavonoid, has demonstrated protective effects against the toxicity induced by 10 nm GNPs in heart tissues.
- The study highlights that smaller GNPs can cause significant cardiac injury and apoptosis, while Qur treatment can mitigate these adverse effects.
Purpose: Gold nanoparticles (GNPs) as pharmaceutical and drug delivery tools exhibited harmful effects on human health and other living species. Quercetin (Qur) reveals various pharmacological effects specially antioxidant, anti-inflammatory and antiapoptotic. This study is directed to investigate hepatotoxicity of GNPs, in addition, to assess the impact of Qur in mitigating the toxicological effects of GNPs.
View Article and Find Full Text PDFBackground: Although, gold nanoparticles (GNPs) are attracting more and more attention due to their ease of synthesis, modification, and great potential value in biomedical applications, exhibited harmful effects on human health and other living species. Quercetin (Qur) clarifies diverse pharmacological effects, especially anti-inflammatory, antiapoptotic, and antioxidant ones.
Aim: This study aimed to evaluate the probable nephrotoxicity induced by different diameters of sphere GNPs, as well as the nephroprotective role of Qur.