serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance.

The global incidence of serovar Schwarzengrund has risen in recent years. This serotype has been isolated from poultry, retail meat, and other food products, leading to multiple outbreaks. Alongside the increase in infections, there are growing concerns about the increasing levels of antimicrobial resistance (AMR) among Schwarzengrund strains.

Sulfide-rich continental roots at cratonic margins formed by carbonated melts.

The cratonic crust contains abundant mineral deposits of metals such as gold, copper and rare earths and is underlain by a thick mantle lithosphere rich in the volatiles carbon, sulfur and water. Although volatiles are known to be key components in metallogenesis, how and where they are distributed in the cratonic lithosphere mantle and their role in the initial enrichment of metals have not been sufficiently explored. Here we compile sulfur and copper contents of global cratonic peridotites, identifying sulfide-rich and copper-rich continental roots at depths of 160-190 km at cratonic margins.

The PH domain in the ArfGAP ASAP1 drives catalytic activation through an unprecedented allosteric mechanism.

ASAP1 is a multidomain Arf GTPase-activating protein (ArfGAP) that catalyzes GTP hydrolysis on the small GTPase Arf1 and is implicated in cancer progression. The PH domain of ASAP1 enhances its activity greater than 7 orders of magnitude but the underlying mechanisms remain poorly understood. Here, we combined Nuclear Magnetic Resonance (NMR), Molecular Dynamic (MD) simulations and mathematical modeling of functional data to build a comprehensive structural-mechanistic model of the complex of Arf1 and the ASAP1 PH domain on a membrane surface.

Factors influencing the effectiveness of nature-based interventions (NBIs) aimed at improving mental health and wellbeing: An umbrella review.

Several systematic reviews support nature-based interventions (NBIs) as a mechanism of enhancing mental health and wellbeing. However, the available evidence for the effectiveness of these interventions is fragmentary and mixed. The heterogeneity of existing evidence and significant fragmentation of knowledge within the field make it difficult to draw firm conclusions regarding the effectiveness of NBIs.

Cross-linked chitosan as biomacromolecular adsorbents for adsorption of precious metal-chloride complexes from aqueous media.

Precious metal recovery from secondary sources has received significant attention due to the reduced availability of precious metals from conventional sources. Herein, chitosan (CHT) was modified via cross-linking with glutaraldehyde (glu) to yield CHT-glu adsorbents with improved physicochemical and adsorption properties with precious metal ions (Au(III) and Pd(II)). CHT-glu adsorbents were prepared at variable glu ratios and characterized via complementary spectral (IR, C solids NMR, XPS) and thermogravimetry methods.

Causes, patterns, and epidemiology of tattoo-associated infections since 1820.

Despite increased awareness and public health initiatives, the incidence of microbial infections related to tattoos has increased since 2000. Building on the first paper in this two-part Series, which detailed the microbiological aspects of tattoo-related infections over the past two centuries from 1820 to 2023, this second paper describes the patterns, causes, and other related epidemiological factors of these infections. Since 2000, bacterial outbreaks, particularly those caused by non-tuberculous mycobacteria, have increased, prompting a re-evaluation of tattoos as a serious public health risk.

Microbiology of tattoo-associated infections since 1820.

The increasing popularity of tattoos parallels the rise in microbial infections associated with tattooing. This two-part Series provides a comprehensive overview of microbial infections linked to tattoos dating back to 1820. This first paper in the Series particularly emphasises the changing landscape of infections since 2000, a period marked by enhanced public health regulations and growing awareness.

Gondwanan relic or recent arrival? The biogeographic origins and systematics of Australian tarantulas.

The composition of Australia's fauna and flora has been largely assembled by two biogeographic processes, vicariance and long-distance dispersal and establishment. These patterns can be observed today through the survival of Gondwanan lineages contrasted with relatively recent colonization from south-east Asia, respectively. In general, the post-Gondwanan immigrant lineages from south-east Asia are taxa with traits that facilitate dispersal.

Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile.

The role of microbes and their metabolites in modulating tuft cell (TC) dynamics in the large intestine and the relevance of this pathway to infections is unknown. Here, we uncover that microbiome-driven colonic TC hyperplasia protects against Clostridioides difficile infection. Using selective antibiotics, we demonstrate increased type 2 cytokines and TC hyperplasia in the colon but not in the ileum.

Implementing verifiable oncological imaging by quality assurance and optimization (i‑Violin) : Protocol for a European multicenter study.

Background: Advanced imaging techniques play a pivotal role in oncology. A large variety of computed tomography (CT) scanners, scan protocols, and acquisition techniques have led to a wide range in image quality and radiation exposure. This study aims at implementing verifiable oncological imaging by quality assurance and optimization (i-Violin) through harmonizing image quality and radiation dose across Europe.

Salmonella enterica virulence databases and bioinformatic analysis tools development.

Salmonella enterica, a prominent foodborne pathogen, contributes significantly to global foodborne illnesses annually. This species exhibits significant genetic diversity, potentially impacting its infectivity, disease severity, and antimicrobial resistance. Whole genome sequencing (WGS) offers comprehensive genetic insights that can be utilized for virulence assessment.

Comprehensive Codified Algorithms to Identify the Underestimated Burden of Hidradenitis Suppurativa in the United States.

Introduction: Hidradenitis suppurativa (HS) is a painful, inflammatory skin disease associated with a high disease burden and long diagnostic delay. Prevalence estimates of HS vary widely in the literature owing to differing estimation methodologies. This study aimed to apply stepwise algorithms to estimate the prevalence of possible/diagnosed cases of HS in the US.

Coupling antitoxins and blue/white screening with /resolvase mutation as a strategy for spp. plasmid curing.

Unlabelled: Despite the dissemination of multidrug resistance plasmids, including those carrying virulence genes in spp., efficient plasmid curing tools are lacking. Plasmid partitioning and multimer resolution systems are attractive targets for plasmid cure.

The acquired gene cluster in mediates resistance to copper.

The pervasive environmental metal contamination has led to selection of heavy-metal resistance genes in bacteria. The and clusters are located on a mobile genetic element and linked to heavy-metal resistance. These clusters have been found in serovars isolated from human clinical cases and foods of animal origin.

Altered Corticospinal and Intracortical Excitability After Stroke: A Systematic Review With Meta-Analysis.

Background: Intracortical inhibitory/faciliatory measures are affected after stroke; however, the evidence is conflicting.

Objective: This meta-analysis aimed to investigate the changes in motor threshold (MT), motor evoked potential (MEP), short-interval intracortical inhibition (SICI), and intracortical facilitation (ICF), and identify sources of study variability using a machine learning approach.

Methods: We identified studies that objectively evaluated corticospinal excitability and intracortical inhibition/facilitation after stroke using transcranial magnetic stimulation.

Understanding the experiences of receiving and providing maternity care for autistic adults: A Multi-perspectival Interpretative Phenomenological Analysis study.

Autistic mothers may experience unique challenges when accessing maternity care. A better understanding of the experience of autistic mothers and maternity care professionals would help to create opportunities to support better maternity care. In this study, we interviewed autistic mothers and professional midwives, living and working across the United Kingdom and Ireland.

Complete genome sequences of CP201 isolated from an asymptomatic rhesus monkey ().

is a leading cause of human gastroenteritis. The genome sequence of CP201 from an asymptomatic rhesus monkey, , consists of one chromosome (3,241,413 bp; 30.22% G + C) and one plasmid (92,983 bp; 28.

Transcriptomic analyses of a pair following exposure to tetracycline during conjugation experiments.

Antimicrobial exposure can potentially lead to increased antimicrobial resistance plasmid transfer. Sequencing data were collected from the RNA of pairs of and exposed or not exposed to tetracycline over time to determine differences in transcription-associated tetracycline exposure during conjugation experiments.

"That Was an Eye Opener for Me": Mixed-Methods Outcomes Educating Texas Community Health Workers on HPV Vaccination Using Project ECHO.

Human papillomavirus (HPV) is known to cause six different types of cancer. HPV vaccination can prevent over 90% of these cancers. Community health workers (CHWs) have the potential to drive HPV vaccination demand through education and navigation by addressing vaccine hesitancy and dis/misinformation and by reaching non-English speaking, vulnerable, or rural populations.

Adsorption of β-Lactoglobulin on Thiol-Functionalized Mesoporous Silica.

SBA-15 mesoporous materials were synthesized with different pore sizes (5 and 10 nm) and thiol-functionalized groups and then characterized to describe their ability to differentially adsorb β-lactoglobulin (BLG), a globular protein with an ellipsoid shape measuring 6.9 nm in length and 3.6 nm in width.

Minimal dose CT for left ventricular ejection fraction and combination with chest-abdomen-pelvis CT.

Objectives: This prospective study tested the diagnostic accuracy, and absolute agreement with MRI of a low-dose CT protocol for left ventricular ejection fraction (LVEF) measurement. Furthermore we assessed its potential for combining it with Chest-Abdomen-Pelvis CT (CAP-CT) for a one-stop examination.

Materials & Methods: Eighty-two patients underwent helical low-dose CT.

Quantifying uncertainty in trans-membrane stresses and moments in simulation.

The lateral stress profile of a lipid bilayer constitutes a valuable link between molecular simulation and mesoscopic elastic theory. Even though it is frequently calculated in simulations, its statistical precision (or that of observables derived from it) is often left unspecified. This omission can be problematic, as uncertainties are prerequisite to assessing statistical significance.