Clinical epidemiologic characterization of orthopaedic and neurological manifestations in children with leukodystrophies.

Background: Leukodystrophies (LKDs) are spectra of clinical conditions characterized primarily by brain white matter abnormalities. Although this condition was previously defined around inherited disorders of the white matter of the brain, current application includes acquired and sporadic conditions and some rare conditions that affect gray matter. Over the past 2 decades, information had become available on the clinical subtypes due to neurodiagnostic imaging and improvement in the genetic studies (cytogenetics and molecular genetics) of LKD.

Testicular cancer incidence trends in the USA (1975-2004): plateau or shifting racial paradigm?

Objective: It has been reported that the incidence of testicular cancer has plateaued in some parts of the USA, especially among non-Hispanic Whites in Los Angeles. Temporal trends analysis was conducted over three decades to assess the evidence for such a plateau, and to examine whether the incidence of testicular cancer remains stable across racial/ethnic groups. This study also investigated the influence of age at diagnosis on the incidence of testicular cancer.

Resorbable anterior cervical plates for single-level degenerative disc disease.

Objective: Resorbable spinal implants have generated increasing interest. There are minimal data in the literature on the use of resorbable anterior cervical plates. The purpose of this study is twofold.