Publications by authors named "Fogg C"
The current opioid crisis has had an unprecedented public health impact. Approved medications for opioid use disorder (OUD) exist, yet their limitations indicate a need for innovative treatments. Limited preliminary clinical studies suggest specific psychedelics might aid OUD treatment, though most clinical evidence remains observational, with few controlled trials.
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- The study aims to address the growing issue of frailty in aging populations by analyzing its incidence, prevalence, and impact on healthcare demand and costs.
- Researchers conducted a retrospective observational study using routine health data from England and Wales to model frailty dynamics and inform service planning.
- Key findings will aid in developing guidelines and tools for healthcare commissioning, ultimately improving care for older people living with frailty.
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View Article and Find Full Text PDFIntroduction: Dementia is a common co-morbidity in older people who require urgent or emergency ambulance attendance and influences clinical decisions and care pathways. Following an initial audit of dementia data and consultation with staff, a specific section (tab) to record dementia was introduced on an ambulance service electronic patient record (ePR). This includes a dementia diagnosis button and a free-text section.
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- Key research findings: Recent studies have showcased innovative approaches and significant discoveries in various fields, pushing the boundaries of knowledge.
- Author contributions: Many contributors have shared unique perspectives and expertise, enriching the academic discourse and fostering collaboration across disciplines.
- Impact on the community: The journals continue to influence both academic circles and public discourse, promoting awareness and providing valuable insights on important societal issues.
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View Article and Find Full Text PDFCyclin-dependent kinase 4 and 6 inhibitors (CDK4/6is) have revolutionized breast cancer therapy. However, <50% of patients have an objective response, and nearly all patients develop resistance during therapy. To elucidate the underlying mechanisms, we constructed an interpretable deep learning model of the response to palbociclib, a CDK4/6i, based on a reference map of multiprotein assemblies in cancer.
View Article and Find Full Text PDFBackground: Frailty becomes more prevalent and healthcare needs increase with age. Information on the impact of frailty on population level use of health services and associated costs is needed to plan for ageing populations.
Aim: To describe primary and secondary care service use and associated costs by electronic Frailty Index (eFI) category.
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