Guess what? Only correct choices forge immediate stimulus-response bindings in guessing scenarios.

A central mechanism of human action control is the prompt binding between actions and the stimuli provoking them. Perceiving the same stimuli again retrieves any bound responses, facilitating their execution. An open question is whether such binding and retrieval only emerges when stimulus-response rules are known upon taking action or also when agents are forced to guess and receive feedback about whether they were successful or not afterward.

Measurements regarding a combined therapy concept for ophthalmic tumors consisting of brachytherapy and x-rays.

We present a novel concept to treat ophthalmic tumors which combines brachytherapy and low-energy x-ray therapy. Brachytherapy withRu applicators is inadequate for intraocular tumors with a height of 7 mm or more. This results from a steep dose gradient, and it is unfeasible to deliver the required dose at the tumor apex without exceeding the maximum tolerable sclera dose of usually 1000 Gy to 1500 Gy.

The relation between learning and stimulus-response binding.

Perception and action rely on integrating or binding different features of stimuli and responses. Such bindings are short-lived, but they can be retrieved for a limited amount of time if any of their features is reactivated. This is particularly true for stimulus-response bindings, allowing for flexible recycling of previous action plans.

Creative thinking does not promote dishonesty.

We assessed the relation of creativity and unethical behaviour by manipulating the thinking style of participants ( = 450 adults) and measuring the impact of this manipulation on the prevalence of dishonest behaviour. Participants performed one of three inducer tasks: the alternative uses task to promote divergent thinking, the remote associates task to promote convergent thinking, or a simple classification task for rule-based thinking. Before and after this manipulation, participants conducted the mind game as a straightforward measure of dishonesty.

Sticky tradition impedes selection of creative ideas.

Creativity is a driving force for human development and has fascinated scholars for centuries. Surprisingly little is known about the cognitive underpinnings of putting creative ideas into action, however. To shed light on this part of the creative process, we tracked how hand movements unfolded when choosing between either a traditional or a creative use of a given object.

Changes of Subjective Symptoms and Tear Film Biomarkers Following Lenticule Extraction.

Purpose: To investigate the influence of lenticule extraction on subjective symptoms and objective biomarkers of dry eye and to clarify relationships between markers and find indicators for subjective symptoms after lenticule extraction.

Methods: Right eyes of myopic patients undergoing lenticule extraction surgery (n = 35) were examined preoperatively and 5 and 90 days postoperatively using established clinical dry eye examination methods (tear film break-up time [BUT], Schirmer test, lissamine green and fluorescein staining, and Ocular Surface Disease Index (OSDI) questionnaire). A patient subset was also examined after 1 year (n = 14).

Clinical applications of circulating tumor DNA in central nervous system lymphoma.

Detection and characterization of circulating tumor DNA (ctDNA) in body fluids have the potential to revolutionize management of patients with lymphoma. Minimal access to malignant DNA through a simple blood draw or lumbar puncture is particularly appealing for CNS lymphomas (CNSL), which cannot be easily or repeatedly sampled without invasive surgeries. Profiling of ctDNA provides a real-time snapshot of the genetic composition in patients with CNSL and enables ultrasensitive quantification of lymphoma burden at any given time point during the course of the disease.

[Survey and reduction of waste production from eye surgery].

Background: The health sector is facing new challenges due to the impact of climate change on health. At the same time, it significantly contributes to our society's climate footprint. Hospitals producing considerable amounts of waste are an important aspect of this burden.

What is left after an error? Towards a comprehensive account of goal-based binding and retrieval.

The cognitive system readily detects and corrects erroneous actions by establishing episodic bindings between representations of the acted upon stimuli and the intended correct response. If these stimuli are encountered again, they trigger the retrieval of the correct response. Thus, binding and retrieval efficiently pave the way for future success.

Integrating nutrition and obesity prevention considerations into institutional investment decisions regarding food companies: Australian investment sector perspectives.

Background: There is growing recognition that current food systems are both unhealthy and unsustainable, and are increasingly shifting toward the supply and marketing of unhealthy, ultra-processed foods and beverages. Large food companies hold substantial power within food systems and present a significant barrier to progress on addressing issues related to nutrition and obesity prevention. Institutional investors (such as pension funds) play a key role in influencing corporate governance and practices, and are increasingly incorporating environmental, social and governance (ESG) considerations within investment decisions.

Feasibility, Method and Early Outcome of Image-Guided Volumetric Modulated Arc Radiosurgery Followed by Resection for AJCC Stage IIA-IIIB High-Risk Large Intraocular Melanoma.

The main objective of this prospective observational study was the characterization of the feasibility and early outcome of image-guided (IG) volumetric modulated arc (VMAT) radiosurgery (SRS) followed by resection for patients with large intraocular melanoma. Our study included consecutive patients with unfavorable-risk melanoma, enrolled in an ophthalmic oncology center. IG-VMAT-SRS was applied by high-resolution 4D image guidance and monitoring.

Commissioning and validation of a novel commercial TPS for ocular proton therapy.

Background: Until today, the majority of ocular proton treatments worldwide were planned with the EYEPLAN treatment planning system (TPS). Recently, the commercial, computed tomography (CT)-based TPS for ocular proton therapy RayOcular was released, which follows the general concepts of model-based treatment planning approach in conjunction with a pencil-beam-type dose algorithm (PBA).

Purpose: To validate RayOcular with respect to two main features: accurate geometrical representation of the eye model and accuracy of its dose calculation algorithm in combination with an Ion Beam Applications (IBA) eye treatment delivery system.

Frankly, My Error, I Don't Give a Damn: Retrieval of Goal-Based but Not Coactivation-Based Bindings after Erroneous Responses.

Previous studies demonstrated binding and retrieval of stimuli and correct responses even for those episodes in which the actual response was wrong (goal-based binding and retrieval). In the current study, we tested whether binding based on a co-activation of stimuli and erroneous responses occurred simultaneously with goal-based binding, which could have been masked by a more efficient retrieval of goal-based bindings in previous studies. In a pre-registered experiment (n = 62), we employed a sequential prime-probe design with a three-choice colour categorisation task.

Binding Error-Induced Control States.

Binding and retrieval of stimulus features, response features, and their attentional weighting tune cognitive processing to situational demands. The two mechanisms promote successful actions, especially in situations in which such actions depend on controlled processing. Here we explored binding and retrieval of attentional control states that follow from erroneous actions.

Binding and Retrieval of Response Durations: Subtle Evidence for Episodic Processing of Continuous Movement Features.

Re-encountering a stimulus retrieves nominally relevant, categorical response features related to previous action decisions in response to this stimulus. Whether binding and retrieval extend to nominally irrelevant, metric features relating to an actual body movement is unknown, however. In two experiments, we thus tested whether repeating target or distractor stimuli across trials retrieves the irrelevant duration of spatial responses to these stimuli.

Integrable Atomtronic Interferometry.

High sensitivity quantum interferometry requires more than just access to entangled states. It is achieved through the deep understanding of quantum correlations in a system. Integrable models offer the framework to develop this understanding.

Post-execution monitoring in dishonesty.

When telling a lie, humans might engage in stronger monitoring of their behavior than when telling the truth. Initial evidence has indeed pointed towards a stronger recruitment of capacity-limited monitoring processes in dishonest than honest responding, conceivably resulting from the necessity to overcome automatic tendencies to respond honestly. Previous results suggested monitoring to be confined to response execution, however, whereas the current study goes beyond these findings by specifically probing for post-execution monitoring.

Cognitive load promotes honesty.

In three experiments, we examined the cognitive underpinnings of self-serving dishonesty by manipulating cognitive load under different incentive structures. Participants could increase a financial bonus by misreporting outcomes of private die rolls without any risk of detection. At the same time, they had to remember letter strings of varying length.

Quantum Chemical Characterization and Design of Quantum Dots for Sensing Applications.

The ability to tune the optoelectronic properties of quantum dots (QDs) makes them ideally suited for the use as fluorescence sensing probes. The vast structural diversity in terms of the composition and size of QDs can make designing a QD for a specific sensing application a challenging process. Quantum chemical calculations have the potential to aid this process through the characterization of the properties of QDs, leading to their design.

Interacting bosons in a triple well: Preface of many-body quantum chaos.

Systems of interacting bosons in triple-well potentials are of significant theoretical and experimental interest. They are explored in contexts that range from quantum phase transitions and quantum dynamics to semiclassical analysis. Here, we systematically investigate the onset of quantum chaos in a triple-well model that moves away from integrability as its potential gets tilted.

Error cancellation.

The human cognitive system houses efficient mechanisms to monitor ongoing actions. Upon detecting an erroneous course of action, these mechanisms are commonly assumed to adjust cognitive processing to mitigate the error's consequences and to prevent future action slips. Here, we demonstrate that error detection has far earlier consequences by feeding back directly onto ongoing motor activity, thus cancelling erroneous movements immediately.

Latest Trends in Investing for Improved Nutrition and Obesity Prevention.

Purpose Of Review: The aim of this paper is to summarise current trends and new developments with regard to institutional investor actions related to nutrition and obesity prevention.

Recent Findings: Investor-related activity related to improving population diets is building, with several recent initiatives aiming to accelerate achievement of global nutrition goals. There is increasing civil society and investor activism focused on leveraging investor influence to improve nutrition-related food company actions.

Goal-Based Binding of Irrelevant Stimulus Features for Action Slips.

Binding between representations of stimuli and actions and later retrieval of these compounds provide efficient shortcuts in action control. Recent observations indicate that these mechanisms are not only effective when action episodes go as planned, but they also seem to be at play when actions go awry. Moreover, the human cognitive system even corrects traces of error commission on the fly because it binds the intended but not actually executed response to concurrent task-relevant stimuli, thus enabling retrieval of a correct, but not actually executed response when encountering the stimulus again.