Publications by authors named "Fnu Chesta"

Article Synopsis
  • * The analysis included data from 81 articles and indicated that the overall incidence of treatment-related pancreatitis was low (0.68% for any-grade, 0.32% for grade 3-5), but the addition of ICIs significantly increased these rates.
  • * Treatment outcomes showed that glucocorticoids were commonly used, while a high percentage of patients (76.5%) had to discontinue ICI therapy due to these adverse events, indicating important clinical implications for managing ICI-related pancreatitis.
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Phospholipase A2 receptor (PLA2R)-associated membranous nephropathy is an important cause of nephrotic syndrome that can lead to a variety of systemic manifestations. Chylous ascites and bilateral renal vein thrombosis are rare manifestations in adult nephrotic syndrome, and there have been no reported cases demonstrating both chylous ascites and bilateral renal vein thrombosis in patients with PLA2R-associated membranous nephropathy. Here, we report the first case of PLA2R-associated membranous nephropathy complicated by renal vein thrombosis and chylous ascites successfully treated with anticoagulation and rituximab.

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Background: Obesity could increase the risk of Barrett's esophagus (BE). Roux-en-Y gastric bypass (RYGB) could alter the natural course of BE. Data on BE progression after RYGB are scarce.

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Management of malignant gastrointestinal obstruction (MGIO) is more challenging in the presence of peritoneal carcinomatosis (PC). Outcomes data to guide the management of MGIO with PC are lacking. We aimed to compare the clinical outcomes and adverse events between endoscopic and surgical palliation and identify predictors of stent success in patients with MGIO with PC.

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Background: Roux-en-Y gastric diversion (RNYG) is an alternative approach for patients with persistent or recurrent gastroesophageal reflux disease (GERD) after surgical fundoplication, especially in patients with esophageal dysmotility or morbid obesity, because redo fundoplication could offer unfavorable outcomes.

Objective: To evaluate long-term outcomes of RNYG for failed fundoplication and its impact on esophageal function.

Setting: A retrospective cohort study and a systematic review.

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