Publications by authors named "Fnu Avanteeka"
Association of Depression With Myocardial Infarction With Non-obstructive Coronary Arteries: A Systematic Review.
J Community Hosp Intern Med Perspect
January 2024
This systematic review examined the association between depression and myocardial infarction with non-obstructive coronary arteries (MINOCA). A comprehensive literature search was conducted using electronic databases, resulting in the inclusion of six small case-control and cohort studies reported from Spain, Australia, China, and Pakistan. The studies included various study designs, such as cohort studies, case-control studies, and prospective cohort studies.
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- The meta-analysis compared the safety and efficacy of angiotensin receptor neprilysin inhibitors (ARNI) against angiotensin receptor blockers (ARBs) and angiotensin-converting-enzyme inhibitors (ACEi) in heart failure with reduced ejection fraction (HFrEF).
- Ten studies were analyzed, revealing that ARNI treatment significantly reduced all-cause mortality and cardiovascular death, but did not show a difference in ejection fraction changes or heart failure hospitalizations compared to control groups.
- However, there was a notable increase in the risk of hypotension among patients taking ARNI, suggesting a need for further research on ARNI usage and its side effects in heart failure patients.
Article Synopsis
- This meta-analysis investigates the effectiveness and safety of low-dose versus standard-dose recombinant tissue plasminogen activators (r-tPA) for treating acute ischemic stroke, following MOOSE guidelines.
- Researchers systematically searched databases for relevant studies from 2010 to 2023, focusing on outcomes like favorable recovery scores, mortality rates, and instances of intracerebral hemorrhage.
- Results show no significant difference in safety outcomes between the two dosage groups, but a notably better recovery rate (favorable outcomes) for patients receiving the standard-dose r-tPA.