Two dimensional echocardiographic similarity of Fabry's disease to cardiac amyloidosis: a function of ultrastructural analogy?

A 53-year-old man with Fabry's disease was studied by echocardiography. Both M-mode and two dimensional echocardiographic examinations produced findings indistinguishable from those previously described as virtually diagnostic of cardiac amyloidosis. Possible causes for the "granular sparkling" appearance and clinical implications of the similarities were discussed.

Acute electrophysiologic effects of nadolol.

The acute effects of intravenous nadolol (0.01 and 0.02 mg/kg) on cardiac electrophysiologic parameters were assessed with His bundle recording and programmed atrial stimulation.

Acute coronary insufficiency - coronary occlusion after intermittent ischemic attacks.

We used angiography in a prospective study of the coronary circulation in patients with acute coronary insufficiency. Reversible ST-T changes during the acute illness corresponded anatomically with severely narrowed coronary arteries (80 to 95 per cent stenosis). Angiograms repeated four months later showed new complete occlusions in nine of 30 severely stenotic arteries.

Myocardial oxygen supply in left ventricular hypertrophy and coronary heart disease.

Coronary arteriolar dilation adjusts blood flow according to local fluctuating metabolic needs of the myocardium. Because of high extravascular compression during systole, the subendocardial layer of the left ventricle is especially dependent on the duration and the perfusion pressure of the diastolic period. In patients with obstructive coronary artery disease, regional arteriolar dilation is utilized to compensate for focal arterial stenoses.