Functional characterization of the cannabinoid receptors 1 and 2 in zebrafish larvae using behavioral analysis.

Rationale: The endocannabinoid system (ECS) comprises the cannabinoids anandamide and 2-arachidonoylglycerol and the cannabinoid receptors 1 and 2 (Cnr1 and Cnr2). The function of these receptors in relation to zebrafish larval behavior is poorly understood, even though the zebrafish larva has become a versatile animal model in biomedical research.

Objectives: The objective of the present study is to characterize the function of Cnr1 and Cnr2 in relation to behavior in zebrafish.