Publications by authors named "Florian Zores"

Importance: Although patients with myocarditis after COVID-19 mRNA vaccination appear to have a good prognosis near hospital discharge, their longer-term prognosis and management remain unknown.

Objective: To study the cardiovascular complications of post-COVID-19 mRNA vaccination myocarditis and other types of myocarditis during an 18-month follow-up, as well as disease management based on a study of the frequency of medical procedures and drug prescriptions.

Design, Setting, And Participants: In this cohort study based on the French National Health Data System, all individuals aged 12 to 49 years hospitalized for myocarditis in France between December 27, 2020, and June 30, 2022, were identified.

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  • There is ongoing debate about the effectiveness of salt-restricted diets in managing heart failure, with current dietary guidelines lacking consistency and supporting evidence.
  • The OFICSel observatory collected data from 2822 patients hospitalized for heart failure, examining the relationship between cardiologists' dietary recommendations and patients’ understanding and adherence to these diets.
  • Findings reveal that while 90% of patients received a recommendation for a diet with less than 6g of salt per day, only 33% adhered to it, and restrictive diets increased the perceived burden on patients, indicating a need for more evidence-based dietary guidelines.
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  • Acute heart failure (AHF) is a serious condition that causes about 5% of emergency hospital admissions in Europe, with the study involving 793 patients, mostly men around 72 years old.
  • Many patients experienced symptoms like dyspnea and lower limb edema before seeking help, with about half showing symptoms for over 15 days prior to hospitalization.
  • Referral methods varied, with emergency services often called during acute symptoms, while cardiologists were typically consulted for longer-standing issues; the study recommends enhancing AHF treatment networks in the French healthcare system for better patient care.
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Physical activity is important in heart failure to improve functional capacity, quality of life and prognosis, and is a class IA recommendation in the European Society of Cardiology guidelines (Ponikowski et al., 2016). The benefits of exercise training are widely recognized.

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Aims: Pathophysiology of reflex syncope is not fully understood but a vagal overactivity might be involved in this syncope. Previously, overexpression of muscarinic M2 receptors and acetylcholinesterase was found in particular in the heart and in lymphocytes of rabbits with vagal overactivity as well as in hearts of Sudden Infant Death Syndromes. The aim of this present study was to look at M2 receptor expression in blood of patients with reflex syncope.

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Pulmonary hypertension (PH) is a common and severe complication of heart failure (HF). Consequently, HF is the leading cause of PH. For many years, specialists have attempted to better understand the pathophysiology of PH in HF, to define its prevalence and its impact on prognosis in order to improve the therapeutic management of these patients.

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Cardiac output (CO) is often desirable for assessing the hemodynamic condition of a patient, especially in critically ill cardiac patients. Various noninvasive methods are available for this purpose. Inert gas rebreathing (IGR) and 2D-Doppler echocardiography methods have been validated.

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