Publications by authors named "Florian Putre"
Article Synopsis
- - Previous studies hinted that medications like statins, metformin, and RAS inhibitors might help with portal hypertension in cirrhotic patients, but their actual impact on serious complications like variceal bleeding needed more research.
- - The study involved 920 cirrhotic patients who underwent endoscopic band ligation for variceal bleeding prevention; it analyzed the effects of the mentioned medications on bleeding rates and survival.
- - The findings showed that the use of statins, metformin, and RAS inhibitors did not significantly lower the rates of initial or recurrent variceal bleeding, nor did they affect mortality rates, suggesting that these medications might not be effective for this specific issue, but they should still be used if clinically indicated for other
Background: Prophylactic endoscopic band ligation (EBL) is used to prevent variceal bleeding in patients with liver cirrhosis. The association of thrombocytopenia, high INR (international normalized ratio) and liver dysfunction with the risk of procedure-related bleeding (PRB) remains debated and recommendations are controversial.
Methods: We analyzed real-life data of cirrhotic patients undergoing elective EBL at two large Viennese centers between Q1/2000-Q1/2018.