Publications by authors named "Florian J Engelken"

Article Synopsis
  • The study aimed to compare gadobutrol and gadoterate meglumine (Gd-DOTA) in assessing breast lesions during MRI by measuring relative enhancement (RE).
  • It involved 52 women who underwent MRI with both contrast agents, analyzing the RE and washout characteristics of identified benign and malignant lesions.
  • Results showed that gadobutrol had significantly higher RE and less washout compared to Gd-DOTA, suggesting it may enhance breast lesion detection and improve MRI specificity.
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Background: The aim of this study was to evaluate imaging-based response to standardized neoadjuvant chemotherapy (NACT) regimen by dynamic contrast-enhanced magnetic resonance mammography (DCE-MRM), whereas MR images were analyzed by an automatic computer-assisted diagnosis (CAD) system in comparison to visual evaluation. MRI findings were correlated with histopathologic response to NACT and also with the occurrence of metastases in a follow-up analysis.

Patients And Methods: Fifty-four patients with invasive ductal breast carcinomas received two identical MRI examinations (before and after NACT; 1.

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Objective: To evaluate whether measurement of strain under static compression in tomosynthesis of a breast-mimicking phantom can be used to distinguish tumor-simulating lesions of different elasticities and to compare the results to values predicted by rheometric analysis as well as results of ultrasound elastography.

Materials And Methods: We prepared three soft breast-mimicking phantoms containing simulated tumors of different elasticities. The phantoms were imaged using a wide angle tomosynthesis system with increasing compression settings ranging from 0 N to 105 N in steps of 15 N.

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Purpose: To demonstrate the feasibility of low-dose photon-counting tomosynthesis in combination with a contrast agent (contrast material-enhanced tomographic mammography) for the differentiation of breast cancer.

Materials And Methods: All studies were approved by the institutional review board, and all patients provided written informed consent. A phantom model with wells of iodinated contrast material (3 mg of iodine per milliliter) 1, 2, 5, 10, and 15 mm in diameter was assessed.

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Rationale And Objectives: The aim of this study was to compare average glandular dose (AGD) in two full-field digital mammography units using different anode/filter combinations.

Materials And Methods: Mammographies of 50 consecutive patients on a mammography system using a tungsten/rhodium (W/Rh) anode/filter combination were retrospectively compared to prior examinations on a different mammography unit using combinations of Molybdenum (Mo) and Rhodium (Rh). To exclude effects of increasing patient age, two prior examinations within 5 years were used.

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Rationale And Objectives: Scanning parameters used in multislice computed tomographic (MSCT) coronary angiography should be adapted to patients' heart rates. The aim of this study was to evaluate the rate of success of a software-assisted scan simulation to determine optimal gantry rotation time prior to MSCT coronary angiography.

Materials And Methods: Data from 218 64-slice MSCT coronary angiographic studies were retrospectively analyzed.

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