Publications by authors named "Florian Graupe"
Article Synopsis
- The study aimed to identify factors affecting prognosis in early adenocarcinomas of the esophagus (eACEs) treated with surgery.
- The analysis of 168 patients revealed that lymph node metastasis (N+) was the key indicator of overall survival and recurrence rates, with a stark contrast between those with and without N+ (47% vs. 5.2% recurrence).
- Findings suggest that while tumor depth is linked to lymph node involvement, there's no clear boundary between deep mucosal and submucosal infiltration, highlighting the need for thorough staging before treatment.
Background: Esophageal adenocarcinoma has attracted more attention among gastroenterologists recently because of its rapidly rising incidence in Western countries. Many new epidemiological findings have been published, and there have been numerous technical advances in diagnostic procedures and in multimodal treatment based on the staging of the disease.
Methods: In this paper, we selectively review the literature on esophageal adenocarcinoma, also considering the evidence-based recommendations contained in the guidelines of the German Society for Digestive and Metabolic Diseases (Deutsche Gesellschaft für Verdauungs- und Stoffwechselkrankheiten, DGVS) as well as the latest data from our own research team.