Identification of Novel Phage Resistance Mechanisms in by Comparative Genomics.

Phages infecting are considered a promising intervention strategy at broiler farms, yet phage sensitivity of naturally occurring poultry isolates is not well studied. Here, we investigated phage sensitivity and identified resistance mechanisms of strains originating from Danish broilers belonging to the most prevalent MLST (ST) types. Determining plaque formation of 51 phages belonging to or showed that 21 out of 31 strains were susceptible to at least one phage.