Data augmentation based on spatial deformations for histopathology: An evaluation in the context of glomeruli segmentation.

Background And Objective: The effective application of deep learning to digital histopathology is hampered by the shortage of high-quality annotated images. In this paper we focus on the supervised segmentation of glomerular structures in patches of whole slide images of renal histopathological slides. Considering a U-Net model employed for segmentation, our goal is to evaluate the impact of augmenting training data with random spatial deformations.