Publications by authors named "Flores-Acosta Rogelio"
Discordant results between genotypic and phenotypic assays (Xpert MTB/RIF vs. BACTEC MGIT 960 system) for detection of RIF-resistant Mycobacterium tuberculosis isolates in a high burden region.
Laniado-Laborín Rafael Muñiz-Salazar Raquel Flores-Acosta Rogelio Félix-Ponce Miroslava Jiménez-Gracia Alejandra-Isabel
Infect Genet Evol
December 2021
Article Synopsis
- A study was conducted on clinical isolates with conflicting results from phenotypic and genotypic tests for rifampin resistance in TB at the Tijuana General Hospital in Mexico.
- Out of 13 isolates tested, discrepancies were found where some were classified as rifampin-susceptible yet resistant according to another test, with DNA sequencing revealing various mutations in some isolates.
- The findings highlighted the importance of further DNA sequencing for accurate diagnoses of rifampin resistance, especially due to cases of heteroresistance and silent mutations.