Publications by authors named "Florentina Lustig"
Histochem Cell Biol
November 2003
Article Synopsis
- The PDGF family consists of dimeric isoforms that are essential for the growth and movement of mesenchymal cells, including both long and short variants.
- Certain PDGF isoforms were found to bind specifically to glycosaminoglycans (GAGs), with long isoforms attaching to both heparan sulfate and chondroitin sulfate, while short isoforms only interacted with heparan sulfate.
- Experiments showed that the binding affinity of PDGF isoforms to GAGs varies, with long isoforms being more effectively inhibited by exogenous GAGs, suggesting that the activity of PDGF at the cell surface may be influenced by the types of GAGs present.
