Publications by authors named "Florent Zittoun"
Neurol Genet
October 2023
Article Synopsis
- CADASIL is a hereditary disease that progressively leads to stroke, cognitive decline, and dependency, caused by mutations in a specific gene, and requires better predictive models to assess patient outcomes and inform clinical trials.*
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- The study aimed to enhance an existing model predicting cognitive performance over three years by incorporating new genetic data related to the location of mutations within the gene.*
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- Results from a study involving 367 patients indicated that those with mutations in a specific genetic domain had a significant additional decrease in cognitive scores, showing the improved predictive capability of the new model compared to previous versions.*
