Synopsis of recent research by authors named "Florent Creusat"
- Florent Creusat's recent research emphasizes the regulatory role of neutrophils during severe viral respiratory infections, highlighting the presence of PD-L1 expressing neutrophils that exhibit suppressive properties, which may compromise the body's antiviral response.
- The studies also explore the interaction between malignant B cells and their microenvironment in B-cell lymphomas, focusing on how the tumor microenvironment influences lymphomagenesis and disease progression, particularly in two specific lymphoma subtypes arising from germinal centers.
- Additionally, Creusat's work has investigated the immune dysfunction caused by severe sepsis, revealing how enteral administration of citrulline can mitigate T cell mitochondrial dysfunction and improve immune responses, drawing parallels to mechanisms observed in cancer-related immune suppression.