This study was carried out to investigate the effects of early administration of losartan on ventricular remodelling (VR) in rabbits with experimental myocardial infarction (MI). New Zealand rabbits underwent left coronary artery ligation. Four groups were analyzed: sham (G1; n = 13), MI (G2; n = 13), sham + Los (G3; n = 13) and MI + Los (G4; n = 13).
View Article and Find Full Text PDFUnlabelled: The objective was to determine whether "hypercontraction" (HC) that occurs at the beginning of reperfusion (R) in stunned myocardium is accompanied by diastolic alterations and determine if the R with low Ca2+. Ringer's solution modifies these alterations. Isolated isovolumic rabbit hearts were divided into 2 groups.
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