Influence of arterial hypotension on fractional flow reserve measurements.

Aims: To assess fractional flow reserve (FFR) variability in case of arterial hypotension in the clinical setting. FFR measurement is supposed to be independent of haemodynamics; there is, however, a strong relationship between trans-stenotic pressure variation and coronary flow. Non-clinical models suggest an inverse relationship between arterial pressure and FFR, but no clinical data have as yet confirmed this hypothesis.