Prediction of moderate and severe toxicities of chemotherapy in older patients with cancer: a propensity weighted analysis of ELCAPA cohort.

Background: Currently available predictive models for chemotherapy-related toxicity are not sufficiently discriminative in older patients with cancer and do not consider moderate toxicities. The purpose of this study was to identify factors associated with moderate and severe chemotherapy toxicities in older patients with cancer.

Materials And Methods: Patients aged 70+ recruited in the prospective ELCAPA cohort were analyzed.

A Two-Step Frailty Assessment Strategy in Older Patients With Solid Tumors: A Decision Curve Analysis.

Purpose: The intended clinical value of frailty screening is to identify unfit patients needing geriatric assessment (GA) and to prevent unnecessary GA in fit patients. These hypotheses rely on the sensitivity and specificity of screening tests, but they have not been verified.

Methods: We performed a cross-sectional analysis of outpatients age ≥ 70 years with prostate, breast, colorectal, or lung cancer included in the ELCAPA cohort study (ClinicalTrials.

[Needs and feelings of caregivers in oncogeriatrics, usefulness of a serious game].

Faced with an ageing population, carers are real allies and partners who are essential to the smooth running of the care of elderly patients. The objective of this study was to analyse their needs in oncogeriatrics, in order to verify the relevance of developing a serious game to support them. Although the need for better support for carers in oncogeriatrics was recognized, they especially value the need for human exchanges.

[The disclosure in geriatric oncology, the benefit of the nurse-doctor partnership].

From the disclosure of a diagnosis to the withdrawal of treatments, an elderly patient with cancer is confronted with numerous disclosures along the care pathway. These become mixed up with the care and support actions. Collaboration and procedures shared between doctors and nurses are essential for the optimised care of the elderly patient and his or her helpers.

Preferences for surrogate designation and decision-making process in older versus younger adults with cancer: A comparative cross-sectional study.

Objective: To compare the preferences of older (≥70 years old) versus younger (<70 years old) cancer patients regarding surrogate designation and decision making.

Methods: A cross-sectional survey. Patient characteristics and information about surrogacy and involvement in decision making were collected.

[Infection, wounds and local treatments].

Infection is the result of complex interactions between bacteria, the host, treatments and the wound environment. The clinical signs and the diagnosis can be obvious, subclinical or relate to an intermediary situation rather than a confirmed infection. Suitable local treatments do not automatically involve the use of antibacterial drugs and consist in washing and draining the wound with appropriate dressings.